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  1. Article

    Open Access

    Elevated brain lactate in schizophrenia: a 7 T magnetic resonance spectroscopy study

    Various lines of evidence suggest that brain bioenergetics and mitochondrial function may be altered in schizophrenia. On the basis of prior phosphorus-31 (31P)-magnetic resonance spectroscopy (MRS), post-mortem ...

    L M Rowland, S Pradhan, S Korenic, S A Wijtenburg, L E Hong… in Translational Psychiatry (2016)

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    Article

    Medial frontal GABA is lower in older schizophrenia: a MEGA-PRESS with macromolecule suppression study

    Gamma-butyric acid (GABA) dysfunction has been implicated in the pathophysiology of schizophrenia and its cognitive deficits. Proton magnetic resonance spectroscopy (MRS) was used to test the hypothesis that o...

    L M Rowland, B W Krause, S A Wijtenburg, R P McMahon, J Chiappelli… in Molecular Psychiatry (2016)

  3. Article

    Open Access

    Alterations in frontal white matter neurochemistry and microstructure in schizophrenia: implications for neuroinflammation

    We investigated in vivo neurochemical markers reflective of neuronal health and glial activation to determine if these could yield clues regarding the reduced fractional anisotropy (FA) of white matter and accele...

    J Chiappelli, L E Hong, S A Wijtenburg, X Du, F Gaston… in Translational Psychiatry (2015)

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