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  1. Article

    Open Access

    Deleterious impact of trivial to severe interstitial pneumonia and emphysema on mortality and acute exacerbation of interstitial pneumonia in patients with lung cancer: a retrospective cohort study

    Interstitial pneumonia and emphysema may complicate patients with lung cancer. However, clinical significance of trivial and mild pulmonary abnormalities remains unclear. In this study, we aimed to investigate...

    Yutaka Tomishima, Atsushi Kitamura, Ryosuke Imai, Sachiko Ohde in BMC Pulmonary Medicine (2024)

  2. Article

    Open Access

    The location of unilateral axillary lymphadenopathy after COVID-19 vaccination compared with that of metastasis from breast cancer without vaccination

    Unilateral axillary lymphadenopathy is known to occur after coronavirus disease (COVID-19) vaccination. Post-vaccination lymphadenopathy may mimic the metastatic lymph nodes in breast cancer, and it is challen...

    Kiyoko Mukai, Hiroko Tsunoda, Ryosuke Imai, Akiko Numata in Japanese Journal of Radiology (2023)

  3. Article

    Open Access

    Intravascular large B-cell lymphoma appearance on dual-energy computed tomography: a case report

    Intravascular large B-cell lymphoma (IVLBCL) is the proliferation of neoplastic B lymphocytes in the vascular space. Since conventional computed tomography (CT) shows nonspecific findings, differentiation betw...

    Daisuke Yamada, Ryosuke Imai, Masaki Matsusako, Yasuyuki Kurihara in BMC Pulmonary Medicine (2023)

  4. Article

    Open Access

    Elevated plasma levels of Krebs von den Lungen-6 and geographic appearance on high-resolution computed tomography are associated with diffuse alveolar damage in autopsy cases of acute respiratory distress syndrome: a retrospective study

    Although diffuse alveolar damage (DAD) is a histopathological hallmark of acute respiratory distress syndrome (ARDS), its detection without lung biopsy is challenging. In patients with ARDS, the specificity of...

    Ryosuke Imai, Daisuke Yamada, Yutaka Tomishima, Tomoaki Nakamura in BMC Pulmonary Medicine (2022)

  5. Article

    Open Access

    Findings of virtual bronchoscopic navigation can predict the diagnostic rate of primary lung cancer by bronchoscopy in patients with peripheral lung lesions

    Despite being minimally invasive, bronchoscopy does not always result in pathological specimens being obtained. Therefore, we investigated whether virtual bronchoscopic navigation (VBN) findings were associate...

    Atsushi Kitamura, Yutaka Tomishima, Ryosuke Imai, Naoki Nishimura in BMC Pulmonary Medicine (2022)

  6. Article

    Open Access

    Visual classification of three computed tomography lung patterns to predict prognosis of COVID-19: a retrospective study

    Quantitative evaluation of radiographic images has been developed and suggested for the diagnosis of coronavirus disease 2019 (COVID-19). However, there are limited opportunities to use these image-based diagn...

    Daisuke Yamada, Sachiko Ohde, Ryosuke Imai, Kengo Ikejima in BMC Pulmonary Medicine (2022)

  7. Article

    Open Access

    Protocol for a systematic review and meta-analysis of studies on the use of brain natriuretic peptide and N-terminal brain natriuretic peptide levels in the diagnosis of cardiopulmonary edema in acute respiratory failure

    Dyspnea with bilateral pulmonary edema is common among patients in emergency departments (EDs) or intensive care units (ICUs). For the initial management of patients with this condition, cardiopulmonary edema ...

    Takero Terayama, Takuya Taniguchi, Ryosuke Imai, Keisuke Anan in Systematic Reviews (2021)

  8. Article

    Open Access

    Comparison of the effects of three types of heating tobacco system and conventional cigarettes on indoor air quality

    Environmental tobacco smoke (ETS) from conventional cigarettes is reported to affect indoor air quality (IAQ) in various real indoor environments. Recently, Japan Tobacco Inc. introduced three types of tobacco...

    Yoshihiro Enomoto, Ryosuke Imai, Keiko Nanjo, Yuichi Fukai in SN Applied Sciences (2021)

  9. Article

    Open Access

    Phase II Clinical Trial of Combination Therapy with Favipiravir and Methylprednisolone for COVID-19 with Non-Critical Respiratory Failure

    The administration of systemic corticosteroids is a key strategy for improving COVID-19 outcomes. However, evidence is lacking on combination therapies of antiviral agents and systemic corticosteroids. The obj...

    Yuichiro Shindo, Yasuhiro Kondoh, Akiko Kada, Yohei Doi in Infectious Diseases and Therapy (2021)

  10. Article

    Open Access

    Author Correction: Mating system evolution and genetic structure of diploid sexual populations of Cyrtomium falcatum in Japan

    Ryosuke Imai, Yoshiaki Tsuda, Atsushi Ebihara, Sadamu Matsumoto in Scientific Reports (2021)

  11. No Access

    Article

    Inferring historical survivals of climate relicts: the effects of climate changes, geography, and population-specific factors on herbaceous hydrangeas

    Climate relicts hold considerable importance because they have resulted from numerous historical changes. However, there are major interspecific variations among the ways by which they survived climate changes...

    Shota Sakaguchi, Yui Asaoka, Daiki Takahashi, Yuji Isagi, Ryosuke Imai in Heredity (2021)

  12. Article

    Open Access

    Mating system evolution and genetic structure of diploid sexual populations of Cyrtomium falcatum in Japan

    Evolution of mating systems has become one of the most important research areas in evolutionary biology. Cyrtomium falcatum is a homosporous fern species native to eastern Asia. Two subspecies belonging to a sexu...

    Ryosuke Imai, Yoshiaki Tsuda, Atsushi Ebihara, Sadamu Matsumoto in Scientific Reports (2021)

  13. No Access

    Article

    Considering evolutionary processes in cycad conservation: identification of evolutionarily significant units within Dioon sonorense (Zamiaceae) in northwestern Mexico

    Cycads are considered to be the most threatened plant group on Earth. Thus, the identification of important biological units for conservation is crucial for their management and protection. Taxonomic studies h...

    José Said Gutiérrez-Ortega, Karen Jiménez-Cedillo in Conservation Genetics (2018)

  14. Article

    Open Access

    Chromatin folding and DNA replication inhibition mediated by a highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex

    Chromatin DNA must be read out for various cellular functions and copied for the next cell division. These processes are targets of many anticancer agents. Platinum-based drugs, such as cisplatin, have been us...

    Ryosuke Imai, Seiji Komeda, Mari Shimura, Sachiko Tamura in Scientific Reports (2016)

  15. Article

    Open Access

    Chromatin as dynamic 10-nm fibers

    Since Flemming described a nuclear substance in the nineteenth century and named it “chromatin,” this substance has fascinated biologists. What is the structure of chromatin? DNA is wrapped around core histone...

    Kazuhiro Maeshima, Ryosuke Imai, Sachiko Tamura, Tadasu Nozaki in Chromosoma (2014)

  16. No Access

    Article

    Carbon Felt-based Bioelectrocatalytic Flow Detectors: Highly Sensitive Amperometric Determination of Hydrogen Peroxide Using Adsorbed Peroxidase and Thionine

    Horseradish peroxidase (HRP) and thionine (TN) were co-adsorbed onto a porous carbon felt (CF), and the resulting HRP and TN-adsorbed CF (HRP-TN-CF) was successfully used as a working electrode unit of a novel...

    Yasushi Hasebe, Ryosuke Imai, Masaki Hirono, Shunichi Uchiyama in Analytical Sciences (2007)