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Article
Open AccessCorrection: Transient increased risk of influenza infection following RSV infection in South Africa: findings from the PHIRST study, South Africa, 2016–2018
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Open AccessTransient increased risk of influenza infection following RSV infection in South Africa: findings from the PHIRST study, South Africa, 2016–2018
Large-scale prevention of respiratory syncytial virus (RSV) infection may have ecological consequences for co-circulating pathogens, including influenza. We assessed if and for how long RSV infection alters th...
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Article
Open AccessShort- and long-read metagenomics of urban and rural South African gut microbiomes reveal a transitional composition and undescribed taxa
Human gut microbiome research focuses on populations living in high-income countries and to a lesser extent, non-urban agriculturalist and hunter-gatherer societies. The scarcity of research between these extr...
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Article
Associations of Father and Adult Male Presence with First Pregnancy and HIV Infection: Longitudinal Evidence from Adolescent Girls and Young Women in Rural South Africa (HPTN 068)
This study, a secondary analysis of the HPTN 068 randomized control trial, aimed to quantify the association of father and male presence with HIV incidence and first pregnancy among 2533 school-going adolescen...
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Article
Open AccessCognitive differences associated with HIV serostatus and antiretroviral therapy use in a population-based sample of older adults in South Africa
Previous clinical studies have reported adverse cognitive outcomes for people living with HIV (PLWH), but there are no population-based studies comparing cognitive function between older PLWH and comparators w...
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Open AccessTraditional healers use of personal protective equipment: a qualitative study in rural South Africa
Traditional healers are frequently exposed to hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) through the widespread practice of traditional “injections”, in which the ...
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Article
Open AccessCognitive function and cardiometabolic disease risk factors in rural South Africa: baseline evidence from the HAALSI study
Evidence on cognitive function in older South Africans is limited, with few population-based studies. We aimed to estimate baseline associations between cognitive function and cardiometabolic disease risk fact...
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Article
Cash Transfers, Young Women’s Economic Well-Being, and HIV Risk: Evidence from HPTN 068
Despite the large interest in economic interventions to reduce HIV risk, little research has been done to show whether there are economic gains of these interventions for younger women and what intermediary ro...
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Article
Education modifies the relationship between height and cognitive function in a cross-sectional population-based study of older adults in Rural South Africa
We aimed to estimate the relationship between height (a measure of early-life cumulative net nutrition) and later-life cognitive function among older rural South African adults, and whether education modified ...
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Article
Open AccessTraditional healer treatment of HIV persists in the era of ART: a mixed methods study from rural South Africa
Human immunodeficiency virus (HIV) substantially contributes to the burden of disease and health care provision in sub-Saharan Africa, where traditional healers play a major role in care, due to both their acc...
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Open AccessCash transfers for HIV prevention: what do young women spend it on? Mixed methods findings from HPTN 068
Social grants have been found to have an impact on health and wellbeing in multiple settings. Who receives the grant, however, has been the subject of discussion with regards to how the money is spent and who ...
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Article
Open AccessEvaluation of the Tsima community mobilization intervention to improve engagement in HIV testing and care in South Africa: study protocol for a cluster randomized trial
HIV transmission can be decreased substantially by reducing the burden of undiagnosed HIV infection and expanding early and consistent use of antiretroviral therapy (ART). Treatment as prevention (TasP) has be...
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HPTN 068: A Randomized Control Trial of a Conditional Cash Transfer to Reduce HIV Infection in Young Women in South Africa—Study Design and Baseline Results
Young women in South Africa are at high risk for HIV infection. Cash transfers offer promise to reduce HIV risk. We present the design and baseline results from HPTN 068, a phase III, individually randomized ...
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Open AccessErratum to: Moving from medical to health systems classifications of deaths: extending verbal autopsy to collect information on the circumstances of mortality
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Open AccessHealth care utilization and outpatient, out-of-pocket costs for active convulsive epilepsy in rural northeastern South Africa: a cross-sectional Survey
Epilepsy is a common neurological disorder, with over 80 % of cases found in low- and middle-income countries (LMICs). Studies from high-income countries find a significant economic burden associated with epil...
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Article
Open AccessMoving from medical to health systems classifications of deaths: extending verbal autopsy to collect information on the circumstances of mortality
Verbal autopsy (VA) is a health surveillance technique used in low and middle-income countries to establish medical causes of death (CODs) for people who die outside hospitals and/or without registration. By v...
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Article
Open AccessChanging use of traditional healthcare amongst those dying of HIV related disease and TB in rural South Africa from 2003 – 2011: a retrospective cohort study
In 2011 there were 5.5 million HIV infected people in South Africa and 71% of those requiring antiretroviral therapy (ART) received it. The effective integration of traditional medical practitioners and biomed...
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Infectious Causes of Epilepsy?
Epilepsy occurs throughout the world, and the prevalence appears to be higher in areas in which the incidence of infections of the central nervous system (CNS) is greater. However, establishing the causal rela...
