18 Result(s)
within
Ruopeng **e
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessRejuvenation as the origin of planar defects in the CrCoNi medium entropy alloy
High or medium- entropy alloys (HEAs/MEAs) are multi-principal element alloys with equal atomic elemental composition, some of which have shown record-breaking mechanical performance. However, the link between...
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Open AccessThe ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer
Neuroendocrine prostate cancer is a rapidly progressive and lethal disease characterized by early visceral metastasis, poor prognosis, and limited treatment options. Uncovering the oncogenic mechanisms could l...
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Article
Open AccessRepressed Blautia-acetate immunological axis underlies breast cancer progression promoted by chronic stress
Chronic stress is a known risk factor for breast cancer, yet the underlying mechanisms are unclear. This study explores the potential involvement of microbial and metabolic signals in chronic stress-promoted b...
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Open AccessValve turning towards on-cycle in cobalt-catalyzed Negishi-type cross-coupling
Ligands and additives are often utilized to stabilize low-valent catalytic metal species experimentally, while their role in suppressing metal deposition has been less studied. Herein, an on-cycle mechanism is...
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Open AccessResurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong
Hong Kong experienced a surge of Omicron BA.2 infections in early 2022, resulting in one of the highest per-capita death rates of COVID-19. The outbreak occurred in a dense population with low immunity towards...
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Open AccessGrain refinement in titanium prevents low temperature oxygen embrittlement
Interstitial oxygen embrittles titanium, particularly at cryogenic temperatures, which necessitates a stringent control of oxygen content in fabricating titanium and its alloys. Here, we propose a structural s...
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Open AccessOff-season RSV epidemics in Australia after easing of COVID-19 restrictions
Human respiratory syncytial virus (RSV) is an important cause of acute respiratory infection with the most severe disease in the young and elderly. Non-pharmaceutical interventions and travel restrictions for ...
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Open AccessHuman seasonal influenza under COVID-19 and the potential consequences of influenza lineage elimination
Annual epidemics of seasonal influenza cause hundreds of thousands of deaths, high levels of morbidity, and substantial economic loss. Yet, global influenza circulation has been heavily suppressed by public he...
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Open AccessGenomic epidemiology of SARS-CoV-2 under an elimination strategy in Hong Kong
Hong Kong employed a strategy of intermittent public health and social measures alongside increasingly stringent travel regulations to eliminate domestic SARS-CoV-2 transmission. By analyzing 1899 genome seque...
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Open AccessElimination of oxygen sensitivity in α-titanium by substitutional alloying with Al
Individually, increasing the concentration of either oxygen or aluminum has a deleterious effect on the ductility of titanium alloys. For example, extremely small amounts of interstitial oxygen can severely de...
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Open AccessDielectric screening in perovskite photovoltaics
The performance of perovskite photovoltaics is fundamentally impeded by the presence of undesirable defects that contribute to non-radiative losses within the devices. Although mitigating these losses has been...
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Open AccessReaction scope and mechanistic insights of nickel-catalyzed migratory Suzuki–Miyaura cross-coupling
Cross-coupling reactions have developed into powerful approaches for carbon–carbon bond formation. In this work, a Ni-catalyzed migratory Suzuki–Miyaura cross-coupling featuring high benzylic or allylic select...
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Article
Open AccessFall Risk Prediction in Multiple Sclerosis Using Postural Sway Measures: A Machine Learning Approach
Numerous postural sway metrics have been shown to be sensitive to balance impairment and fall risk in individuals with MS. Yet, there are no guidelines concerning the most appropriate postural sway metrics to ...
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Article
Open AccessEndolysin LysEF-P10 shows potential as an alternative treatment strategy for multidrug-resistant Enterococcus faecalis infections
Phage-derived lysins can hydrolyse bacterial cell walls and show great potential for combating Gram-positive pathogens. In this study, the potential of LysEF-P10, a new lysin derived from a isolated Enterococcus ...
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Open AccessFrom Mechanistic Study to Chiral Catalyst Optimization: Theoretical Insight into Binaphthophosphepine-catalyzed Asymmetric Intramolecular [3 + 2] Cycloaddition
Density functional M11 was used to study the mechanism and enantioselectivity of a binaphthophosphepine-catalyzed intramolecular [3 + 2] cycloaddition reaction. The computational results revealed that this rea...
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Open AccessStabilization of Two Radicals with One Metal: A Stepwise Coupling Model for Copper-Catalyzed Radical–Radical Cross-Coupling
Transition metal-catalyzed radical–radical cross-coupling reactions provide innovative methods for C–C and C–heteroatom bond construction. A theoretical study was performed to reveal the mechanism and selectiv...
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Open AccessOptimization of hierarchical structure and nanoscale-enabled plasmonic refraction for window electrodes in photovoltaics
An ideal network window electrode for photovoltaic applications should provide an optimal surface coverage, a uniform current density into and/or from a substrate, and a minimum of the overall resistance for a...
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Open AccessLysGH15 kills Staphylococcus aureus without being affected by the humoral immune response or inducing inflammation
The lysin LysGH15, derived from the staphylococcal phage GH15, exhibits a wide lytic spectrum and highly efficient lytic activity against methicillin-resistant Staphylococcus aureus (MRSA). Here, we found that Ly...
