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5 Result(s)

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  1. No Access

    Article

    Interactions between HMG proteins (HMG1/2 and HMG14/17) and human ε-globin gene promoter (ε-promoter)

    High mobility group (HMG) proteins are abundant non-histone proteins in the nuclei of eukaryocytes. It has been shown that HMG proteins may play important roles in the structure and function of chromatin. In t...

    Chunhui Hou, Jian Huang, Shubing Zhang, Ruolan Qian in Chinese Science Bulletin (2002)

  2. No Access

    Article

    Interactions between GATA transcription factors and the DNaseI hypersensitive sites in the human β-globin gene LCR

    In this study, we analyze the binding of nuclear proteins isolated from the hydroxyurea (Hu)-induced and uninduced HEL cells to the DNasel hypersensitive sites III (HS3-14991-14716 bp) and IV(HS4 -18586-18306 ...

    Shubing Zhang, Hui Zhao, Shu Jiang, Ruolan Qian in Chinese Science Bulletin (2000)

  3. No Access

    Article

    CREB is activated in EPO induced HEL cells

    cAMP response element binding protein (CREB) is a transcription factor in nucleus. The activating CREB can specifically bind to the cAMP response element (CRE). The present result showed that erythropoietin (E...

    Chu Jiang, Changyun Gui, Ruolan Qian in Chinese Science Bulletin (2000)

  4. No Access

    Article

    Interactions between the nuclear matrix proteins and the 5′-flankingcis-acting elements of the human ε-globin gene

    An erythroid-specific nuclear matrix protein (termed ε-NMPk) in K562 cells, which can specifically bind to the positive stage-specific regulatory element (ε-PRE II, - 446 - 419 bp) upstream of the human ε-globin ...

    Zhijiang Yan, Ruolan Qian in Chinese Science Bulletin (1999)

  5. No Access

    Article

    HS3 of the mouse β-LCR

    Yi Tang, Ruolan Qian in Chinese Science Bulletin (1997)