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Article
Interactions between HMG proteins (HMG1/2 and HMG14/17) and human ε-globin gene promoter (ε-promoter)
High mobility group (HMG) proteins are abundant non-histone proteins in the nuclei of eukaryocytes. It has been shown that HMG proteins may play important roles in the structure and function of chromatin. In t...
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Article
Interactions between GATA transcription factors and the DNaseI hypersensitive sites in the human β-globin gene LCR
In this study, we analyze the binding of nuclear proteins isolated from the hydroxyurea (Hu)-induced and uninduced HEL cells to the DNasel hypersensitive sites III (HS3-14991-14716 bp) and IV(HS4 -18586-18306 ...
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Article
CREB is activated in EPO induced HEL cells
cAMP response element binding protein (CREB) is a transcription factor in nucleus. The activating CREB can specifically bind to the cAMP response element (CRE). The present result showed that erythropoietin (E...
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Article
Interactions between the nuclear matrix proteins and the 5′-flankingcis-acting elements of the human ε-globin gene
An erythroid-specific nuclear matrix protein (termed ε-NMPk) in K562 cells, which can specifically bind to the positive stage-specific regulatory element (ε-PRE II, - 446 - 419 bp) upstream of the human ε-globin ...
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Article
HS3 of the mouse β-LCR