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Article
Experimental Investigation on Hydraulic Fracture Propagation Behaviors of Coal-Measure Thin Interbedded Rocks
Clarifying the vertical propagation mechanism of hydraulic fractures (HFs) within thin interbedded rocks can provide the fundamental insights into cross-layer behaviors of HFs and valuable guidance for designi...
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Article
Open AccessTargeted metabolomic profiles of serum amino acids are independently correlated with malnutrition in older adults
Malnutrition is a common geriatric syndrome that is closely associated with adverse clinical outcomes and poses significant harm to older adults. Early assessment of nutritional status plays a crucial role in ...
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Article
Geomechanical Properties of Thinly Interbedded Rocks Based on Micro- and Macro-Scale Measurements
Clarifying the geomechanical properties and inherent heterogeneity of layered rocks is essential for predicting fracture morphology and designing hydraulic fracturing pum** schemes. Grid nanoindentation comb...
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Article
Open AccessSpecific lysophosphatidylcholine and acylcarnitine related to sarcopenia and its components in older men
Metabolic profiling may provide insights into the pathogenesis and identification of sarcopenia; however, data on the metabolic basis of sarcopenia and muscle-related parameters among older adults remain incom...
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Article
Fracture Initiation and Morphology of Tight Sandstone by Liquid Nitrogen Fracturing
Hydraulic fracturing is a commonly used stimulation method in develo** tight sandstone reservoirs. Creation of complex fracture networks to enlarge stimulated reservoir volume plays an increasingly significa...
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Article
3D Cutting Force Model of a Stinger PDC Cutter: Considering Confining Pressure and the Thermal Stress
Cutting force prediction of the Stinger PDC cutter is a critically important work for the hybrid PDC bit design, which will directly affect the working stability and rock-breaking efficiency of drill bits. The...
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Article
Open AccessGut bacteria Akkermansia is associated with reduced risk of obesity: evidence from the American Gut Project
Gut bacteria Akkermansia has been shown an anti-obesity protective effect in previous studies and may be used as promising probiotics. However, the above effect may be confounded by common factors, such as sex, a...
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Article
Open AccessSerum branched-chain amino acids are associated with leukocyte telomere length and frailty based on residents from Guangxi longevity county
Branched-chain amino acids (BCAAs) and telomere length are biologically associated with healthy aging. However, the association between them and their interaction on frailty remain unclear in humans. Here, a c...
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Article
Open AccessChanges of upright body posture in the sagittal plane of men and women occurring with aging – a cross sectional study
Body posture is a fundamental indicator for assessing health and quality of life, especially for elderly people. Deciphering the changes in body posture occurring with age is a current topic in the field of ge...
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Article
Open AccessAssociation of serum glycine levels with metabolic syndrome in an elderly Chinese population
Several studies have identified a negative association between serum glycine (Gly) levels and metabolic syndrome (MetS). However, this association has not been fully established in the elderly.
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Article
A simple and precise method to detect sterol esterification activity of lecithin/cholesterol acyltransferase by high-performance liquid chromatography
The measurement of lecithin: cholesterol acyltransferase (LCAT, EC 2.3.1.43) activity is important in high-density lipoprotein (HDL) metabolism study and cardiovascular disease (CVD) risk assessment. However, ...
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Article
Open AccessFractional esterification rate of cholesterol in high-density lipoprotein associates with risk of coronary heart disease
Fractional esterification rate of cholesterol in high-density lipoprotein (FERHDL) has been found to be closely correlated with atherosclerotic dyslipidemia, especially lipoprotein distributions, and is a potenti...
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Article
Open AccessA Comprehensive Model for Real Gas Transport in Shale Formations with Complex Non-planar Fracture Networks
A complex fracture network is generally generated during the hydraulic fracturing treatment in shale gas reservoirs. Numerous efforts have been made to model the flow behavior of such fracture networks. Howeve...
