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  1. Article

    Open Access

    RACK1 facilitates breast cancer progression by competitively inhibiting the binding of β-catenin to PSMD2 and enhancing the stability of β-catenin

    The receptor for activated C kinase 1 (RACK1) is a key scaffolding protein with multifunctional and multifaceted properties. By mediating protein-protein interactions, RACK1 integrates multiple intracellular s...

    Ruinan Tian, Jianfei Tian, **aoyan Zuo, Sixin Ren, He Zhang in Cell Death & Disease (2023)

  2. Article

    Open Access

    Fructose promotes angiogenesis by improving vascular endothelial cell function and upregulating VEGF expression in cancer cells

    Fructose is a very common sugar found in natural foods, while current studies demonstrate that high fructose intake is significantly associated with increased risk of multiple cancers and more aggressive tumor...

    Yanfen Cui, Hui Liu, Zhaosong Wang, He Zhang in Journal of Experimental & Clinical Cancer … (2023)

  3. Article

    Open Access

    Chemotherapy induces ACE2 expression in breast cancer via the ROS-AKT-HIF-1α signaling pathway: a potential prognostic marker for breast cancer patients receiving chemotherapy

    Angiotensin-converting enzyme 2 (ACE2) is a key enzyme of the renin-angiotensin system and a well-known functional receptor for the entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into ho...

    **aoyan Zuo, Sixin Ren, He Zhang, Jianfei Tian in Journal of Translational Medicine (2022)