6 Result(s)
within
Rui Kuang
Bioinformatics
-
Article
Open AccessPredicting and exploring network components involved in pathogenesis in the malaria parasite via novel subnetwork alignments
Malaria is a major health threat, affecting over 40% of the world's population. The latest report released by the World Health Organization estimated about 207 million cases of malaria infection, and about 627...
-
Article
Open AccessSubPatCNV: approximate subspace pattern mining for map** copy-number variations
Many DNA copy-number variations (CNVs) are known to lead to phenotypic variations and pathogenesis. While CNVs are often only common in a small number of samples in the studied population or patient cohort, pr...
-
Article
Open AccessA novel subnetwork alignment approach predicts new components of the cell cycle regulatory apparatus in Plasmodium falciparum
According to the World Health organization, half the world's population is at risk of contracting malaria. They estimated that in 2010 there were 219 million cases of malaria, resulting in 660,000 deaths and a...
-
Article
Open AccessModule-based subnetwork alignments reveal novel transcriptional regulators in malaria parasite Plasmodium falciparum
Malaria causes over one million deaths annually, posing an enormous health and economic burden in endemic regions. The completion of genome sequencing of the causative agents, a group of parasites in the genus Pl...
-
Article
Open AccessSVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Predicting a protein's structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on develo** new representations for protein sequences, cal...
-
Article
Open AccessProtein Ranking by Semi-Supervised Network Propagation
Biologists regularly search DNA or protein databases for sequences that share an evolutionary or functional relationship with a given query sequence. Traditional search methods, such as BLAST and PSI-BLAST, fo...
