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    Article

    Effects of Exercise and Vasodilators on Cerebral Tissue Oxygenation in Pulmonary Hypertension

    Arterial and thromboembolic pulmonary hypertension (PH) lead to arterial hypoxaemia.

    Séverine Müller-Mottet, Florian F. Hildenbrand, Stephan Keusch, Elisabeth Hasler in Lung (2015)

  2. No Access

    Article

    Long-term Effect of Vasodilator Therapy in Pulmonary Hypertension due to COPD: A Retrospective Analysis

    Pulmonary hypertension (PH) due to COPD has dismal prognosis. We reviewed the long-term effect of PH-target therapy in severe PH-COPD.

    Laura Fossati, Séverine Müller-Mottet, Elisabeth Hasler, Rudolf Speich in Lung (2014)

  3. Article

    Open Access

    Experience with exercise right heart catheterization in the diagnosis of pulmonary hypertension: a retrospective study

    Data on exercise pulmonary hemodynamics in healthy people and patients with pulmonary hypertension (PH) are rare. We analyzed exercise right heart catheterization (RHC) data in a symptomatic collective referre...

    Stephan Keusch, Anina Bucher in Multidisciplinary Respiratory Medicine (2014)

  4. Article

    Open Access

    Inflammatory cytokines in pulmonary hypertension

    Pulmonary hypertension is an “umbrella term” used for a spectrum of entities resulting in an elevation of the pulmonary arterial pressure. Clinical symptoms include dyspnea and fatigue which in the absence of ...

    Alexandra Groth, Bart Vrugt, Matthias Brock, Rudolf Speich in Respiratory Research (2014)

  5. Article

    Open Access

    Weaning from intravenous prostanoids and normalization of hemodynamics by long-term imatinib therapy in severe idiopathic pulmonary arterial hypertension

    Introduction Despite new treatment options targeted at its three main pathogenic pathways, prognosis of idiopathic pulmonary arterial hypertension has remained dismal, with 3-year survival rates ...

    Rudolf Speich, Ursula Treder in International Journal of Clinical Pharmacy (2014)

  6. Article

    Open Access

    Reference values for the 6-minute walk test in healthy children and adolescents in Switzerland

    The six-minute walk test (6MWT) is a simple, low tech, safe and well established, self-paced assessment tool to quantify functional exercise capacity in adults. The definition of normal 6MWT in children is esp...

    Silvia Ulrich, Florian F Hildenbrand, Ursula Treder in BMC Pulmonary Medicine (2013)

  7. Article

    Open Access

    The German adaptation of the Cambridge pulmonary hypertension outcome review (CAMPHOR)

    Individuals with precapillary pulmonary hypertension (PH) experience severely impaired quality of life. A disease-specific outcome measure for PH, the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) ...

    Katharina Cima, James Twiss, Rudolf Speich in Health and Quality of Life Outcomes (2012)

  8. Article

    Open Access

    A low resting heart rate at diagnosis predicts favourable long-term outcome in pulmonary arterial and chronic thromboembolic pulmonary hypertension. A prospective observational study

    A low resting heart rate (HR) is prognostically favourable in healthy individuals and in patients with left heart disease. In this study we investigated the impact of HR at diagnosis on long-term outcome in pa...

    Florian F Hildenbrand, Ivan Fauchère, Lars C Huber, Stephan Keusch in Respiratory Research (2012)

  9. Article

    Open Access

    Pulmonary hypertension in patients with Martorell hypertensive leg ulcer: a case control study

    Martorell hypertensive ischemic leg ulcer (Martorell ulcer) is characterized by distinct alterations in the arteriolar wall of subcutaneous vessels, leading to progressive narrowing of the vascular lumen and i...

    Leonardo Glutz von Blotzheim, Felix C Tanner, Georg Noll in Respiratory Research (2012)

  10. Article

    Open Access

    Extensive chronic xanthogranulomatous intra-abdominal inflammation due to Mycoplasma hominis mimicking a malignancy: a case report

    While infectious peritonitis is a common occurrence in patients with liver cirrhosis, Mycoplasma is rarely identified as a causative agent.

    Luc Biedermann, Dominik J Schaer, Matteo Montani in Journal of Medical Case Reports (2009)

  11. Article

    Open Access

    Successful pregnancy in pulmonary arterial hypertension associated with systemic lupus erythematosus: a case report

    Pulmonary arterial hypertension is a complication of systemic lupus erythematosus. Mortality in pregnant patients with pulmonary arterial hypertension related to connective tissue disease is as high as 56%. Th...

    Michael Streit, Rudolf Speich, Manuel Fischler in Journal of Medical Case Reports (2009)

  12. Article

    Open Access

    Peripheral blood B lymphocytes derived from patients with idiopathic pulmonary arterial hypertension express a different RNA pattern compared with healthy controls: a cross sectional study

    Idiopathic pulmonary arterial hypertension (IPAH) is a progressive and still incurable disease. Research of IPAH-pathogenesis is complicated by the lack of a direct access to the involved tissue, the human pul...

    Silvia Ulrich, Laima Taraseviciene-Stewart, Lars C Huber in Respiratory Research (2008)