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  1. Article

    Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19

    Coronavirus disease 2019 (COVID-19) is especially severe in aged populations1. Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are highly effective, but vaccine efficacy is partly co...

    Lok-Yin Roy Wong, Jian Zheng, Kevin Wilhelmsen, Kun Li, Miguel E. Ortiz… in Nature (2022)

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    Article

    The tumor suppressor PTEN has a critical role in antiviral innate immunity

    PTEN functions as a tumor suppressor. Guo and colleagues now find PTEN also serves a critical role in antiviral innate immunity by inducing the production of type I interferon.

    Shun Li, Mingzhu Zhu, Ruangang Pan, Ting Fang, Yuan-Yuan Cao… in Nature Immunology (2016)

  3. Article

    Open Access

    Characterizing and controlling the inflammatory network during influenza A virus infection

    To gain insights into the pathogenesis of influenza A virus (IAV) infections, this study focused on characterizing the inflammatory network and identifying key proteins by combining high-throughput data and co...

    Suoqin **, Yuanyuan Li, Ruangang Pan, **ufen Zou in Scientific Reports (2014)

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