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Article
Antimycotic Drug Discovery in the Age of Genomics
Genomic-based methodologies are increasingly used at all stages of drug development. The most extensive applications have occurred in early drug discovery stages due to advances in technologies that allow for ...
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Article
Twenty-four hour tolbutamide plasma concentration as a phenotypic measure of CYP2C9 activity
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Article
Gemcitabine pharmacokinetics and interaction with paclitaxel in patients with advanced non-small-cell lung cancer
Gemcitabine administered at a fixed dose rate of 10 mg/m2 per min has been reported to achieve plasma steady-state concentrations ranging from 10 to 20 μM in patients with acute leukemia. These concentrations hav...