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  1. No Access

    Article

    Immune-checkpoint inhibition for resectable non-small-cell lung cancer — opportunities and challenges

    Therapeutic strategies harnessing the immune system to eliminate tumour cells have been successfully used for several cancer types, including in patients with advanced-stage non-small-cell lung cancer (NSCLC)....

    Giannis Mountzios, Jordi Remon, Lizza E. L. Hendriks… in Nature Reviews Clinical Oncology (2023)

  2. Article

    Open Access

    Correction to: SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)

    Rosario García-Campelo, Ivana Sullivan… in Clinical and Translational Oncology (2023)

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  3. Article

    Open Access

    SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022)

    Small-cell lung cancer (SCLC) is a highly aggressive malignancy comprising approximately 15% of lung cancers. Only one-third of patients are diagnosed at limited-stage (LS). Surgical resection can be curative ...

    Rosario García-Campelo, Ivana Sullivan… in Clinical and Translational Oncology (2023)

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  4. Article

    Open Access

    SEOM-GEINO clinical guideline of systemic therapy and management of brain central nervous system metastases (2021)

    Central nervous system (CNS) dissemination is a severe complication in cancer and a leading cause of cancer-related mortality. Brain metastases (BMs) are the most common types of malignant intracranial tumors ...

    María Martínez-García, Sonia Servitja Tormo… in Clinical and Translational Oncology (2022)

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  5. No Access

    Article

    Immunotherapy with checkpoint inhibitors in non-small cell lung cancer: insights from long-term survivors

    Immune checkpoint inhibitors (ICIs) targeting the programmed cell death-1 (PD-1)–programmed cell death ligand-1 (PD-L1) axis have shown promising results in non-small cell lung cancer (NSCLC) patients, some of...

    Ernest Nadal, Bartomeu Massuti, Manuel Dómine… in Cancer Immunology, Immunotherapy (2019)

  6. No Access

    Article

    SEOM clinical guidelines for the treatment of small-cell lung cancer

    Ángel Artal Cortés, Manuel Dómine Gómez… in Clinical and Translational Oncology (2010)

  7. No Access

    Article

    Expression of Wnt gene family and frizzled receptors in head and neck squamous cell carcinomas

    Genes of the Wnt and Frizzled class, expressed in HNSCC tissue and cell lines, have an established role in cell morphogenesis and differentiation, and also they have oncogenic properties. We studied Wnt and Fz...

    Silvia Maria Díaz Prado, Vanessa Medina Villaamil… in Virchows Archiv (2009)

  8. No Access

    Article

    Clinical-molecular factors predicting response and survival for tyrosine-kinase inhibitors

    The development of drugs with special mechanisms of action, such as tyrosine kinase inhibitors (TKIs), means that new clinical-molecular questions are being examined and this will help us to better select from...

    Mariano Provencio, Rosario García-Campelo… in Clinical and Translational Oncology (2009)

  9. No Access

    Article

    Origin of renal cell carcinomas

    Cancer is a heritable disorder of somatic cells: environment and heredity are both important in the carcinogenic process. The primal force is the “two hits” of Knudson’s hypothesis, which has proved true for m...

    Manuel Valladares Ayerbes… in Clinical and Translational Oncology (2008)