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    Article

    Rational patient selection for catheter ablation of atrial fibrillation

    During the past decade, catheter ablation of atrial fibrillation has been progressively used for the treatment of drug-refractory patients. As experience and technique have evolved, patient selection criteria ...

    Roopinder K. Sandhu, Luigi Di Biase, William R. Lewis in Current Cardiology Reports (2009)

  2. Article

    Open Access

    A case report of QT prolongation with glycopyrronium bromide in a patient with chronic tamoxifen use

    Glycopyrronium bromide has recently been approved as a once daily maintenance inhalation therapy for moderate to severe chronic obstructive pulmonary disease (COPD). Efficacy and safety trial data have found r...

    Michael H. Chiu, Nawaf S. Al-Majed, Ryan Stubbins, Dylan Pollmann in BMC Research Notes (2016)

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    Article

    Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

    Patrick Ellinor and colleagues report meta-analyses of common and rare variant association studies for atrial fibrillation across multiple populations. They identify 12 new loci, some of which implicate genes ...

    Ingrid E Christophersen, Michiel Rienstra, Carolina Roselli, **aoyan Yin in Nature Genetics (2017)

  4. Article

    Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

    Nat. Genet.; 10.1038/ng.3843; corrected online 11 May 2017 In the version of this article initially published online, the authors were incorrectly defined as members of the AFGen consortium in the author list....

    Ingrid E Christophersen, Michiel Rienstra, Carolina Roselli, **aoyan Yin in Nature Genetics (2017)

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    Article

    Multi-ethnic genome-wide association study for atrial fibrillation

    Atrial fibrillation (AF) affects more than 33 million individuals worldwide1 and has a complex heritability2. We conducted the largest meta-analysis of genome-wide association studies (GWAS) for AF to date, consi...

    Carolina Roselli, Mark D. Chaffin, Lu-Chen Weng, Stefanie Aeschbacher in Nature Genetics (2018)

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    Article

    Atomoxetine for suppression of vasovagal syncope

    Vasovagal syncope (VVS) is a common clinical condition with few effective medical therapies. The study aimed to evaluate the effectiveness of atomoxetine in suppressing syncope in patients with recurrent VVS.

    Robert S. Sheldon, Colette Seifer, Ratika Parkash in Clinical Autonomic Research (2023)

  7. Article

    Open Access

    Towards artificial intelligence-based learning health system for population-level mortality prediction using electrocardiograms

    The feasibility and value of linking electrocardiogram (ECG) data to longitudinal population-level administrative health data to facilitate the development of a learning healthcare system has not been fully ex...

    Weijie Sun, Sunil Vasu Kalmady, Nariman Sepehrvand, Amir Salimi in npj Digital Medicine (2023)

  8. Article

    Open Access

    Deep learning-based electrocardiographic screening for chronic kidney disease

    Undiagnosed chronic kidney disease (CKD) is a common and usually asymptomatic disorder that causes a high burden of morbidity and early mortality worldwide. We developed a deep learning model for CKD screening...

    Lauri Holmstrom, Matthew Christensen, Neal Yuan in Communications Medicine (2023)

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    Article

    Kidney function monitoring and trajectories in patients with atrial fibrillation

    Atrial fibrillation (AF) and chronic kidney disease (CKD) frequently co-exist. The frequency of kidney monitoring and range of kidney function in patients with AF in clinical practice are uncertain.

    Nathaniel M. Hawkins, Natasha Wiebe in Clinical and Experimental Nephrology (2023)

  10. Article

    Open Access

    Deep learning evaluation of echocardiograms to identify occult atrial fibrillation

    Atrial fibrillation (AF) often escapes detection, given its frequent paroxysmal and asymptomatic presentation. Deep learning of transthoracic echocardiograms (TTEs), which have structural information, could he...

    Neal Yuan, Nathan R. Stein, Grant Duffy, Roopinder K. Sandhu in npj Digital Medicine (2024)