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Article
Kidney function monitoring and trajectories in patients with atrial fibrillation
Atrial fibrillation (AF) and chronic kidney disease (CKD) frequently co-exist. The frequency of kidney monitoring and range of kidney function in patients with AF in clinical practice are uncertain.
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Article
Open AccessAssociations of body mass index, fasting insulin, and inflammation with mortality: a prospective cohort study
Obesity is often considered to increase the risk for premature mortality. Higher fasting insulin and c-reactive protein are associated with higher body mass index (BMI) and all-cause mortality, so may confound...
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Protocol
Evidence-Based Decision-Making 2: Systematic Reviews and Meta-Analysis
The number of studies published in the biomedical literature has dramatically increased over the last few decades. This massive proliferation of literature makes clinical medicine increasingly complex, and inf...
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Article
Open AccessCorrection to: Methods for identifying 30 chronic conditions: application to administrative data
Following publication of the original manuscript [1], the authors noted several errors in Table 1. Details of the requested corrections are shown below:
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Article
A cardiac magnetic resonance imaging study of long-term and incident hemodialysis patients
The cardiovascular morphology and function in long-term survivors of hemodialysis are not well described.
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Article
Open AccessJoint associations of obesity and estimated GFR with clinical outcomes: a population-based cohort study
Despite the interrelationships between obesity, eGFR and albuminuria, few large studies examine how obesity modifies the association between these markers of kidney function and adverse clinical outcomes.
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Article
Open AccessPhysical Activity In Renal Disease (PAIRED) and the effect on hypertension: study protocol for a randomized controlled trial
The prevalence of hypertension among people with chronic kidney disease is high with over 60% of people not attaining recommended targets despite taking multiple medications. Given the health and economic impl...
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Article
Open AccessA comparison of temporal artery thermometers with internal blood monitors to measure body temperature during hemodialysis
Thermometers that measure core (internal) body temperature are the gold standard for monitoring temperature. Despite that most modern hemodialysis machines are equipped with an internal blood monitor that meas...
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Article
Open AccessCatheter-related blood stream infections in hemodialysis patients: a prospective cohort study
For people requiring hemodialysis, infectious mortality is independently associated with geographic distance from a nephrologist. We aimed to determine if differential management of catheter-related blood stre...
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Article
Open AccessService-integration approaches for families with low income: a Families First Edmonton, community-based, randomized, controlled trial
Increasing access to health and social services through service-integration approaches may provide a direct and sustainable way to improve health and social outcomes in low-income families.
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Article
Open AccessMethods for identifying 30 chronic conditions: application to administrative data
Multimorbidity is common and associated with poor clinical outcomes and high health care costs. Administrative data are a promising tool for studying the epidemiology of multimorbidity. Our goal was to derive ...
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Article
Open AccessTrace element supplementation in hemodialysis patients: a randomized controlled trial
People with kidney failure are often deficient in zinc and selenium, but little is known about the optimal way to correct such deficiency.
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Protocol
Evidence-Based Decision-Making 2: Systematic Reviews and Meta-analysis
The number of studies published in the biomedical literature has dramatically increased over the last few decades. This massive proliferation of literature makes clinical medicine increasingly complex, and inf...
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Article
Open AccessThe protocol for the Families First Edmonton trial (FFE): a randomized community-based trial to compare four service integration approaches for families with low-income
Families with low incomes experience an array of health and social challenges that compromise their resilience and lead to negative family outcomes. Along with financial constraints, there are barriers associa...
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Article
Open AccessA systematic review on the effect of sweeteners on glycemic response and clinically relevant outcomes
The major metabolic complications of obesity and type 2 diabetes may be prevented and managed with dietary modification. The use of sweeteners that provide little or no calories may help to achieve this object...
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Article
Open AccessDesign and implementation of the canadian kidney disease cohort study (CKDCS): A prospective observational study of incident hemodialysis patients
Many nephrology observational studies use renal registries, which have well known limitations. The Canadian Kidney Disease Cohort Study (CKDCS) is a large prospective observational study of patients commencing...
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Article
Open AccessOverview of the Alberta Kidney Disease Network
The Alberta Kidney Disease Network is a collaborative nephrology research organization based on a central repository of laboratory and administrative data from the Canadian province of Alberta.
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Article
Open AccessTrace elements in hemodialysis patients: a systematic review and meta-analysis
Hemodialysis patients are at risk for deficiency of essential trace elements and excess of toxic trace elements, both of which can affect health. We conducted a systematic review to summarize existing literatu...
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Article
Open AccessTreatment in the pediatric emergency department is evidence based: a retrospective analysis
Our goal was to quantify the evidence that is available to the physicians of a pediatric emergency department (PED) in making treatment decisions. Further, we wished to ascertain what percentage of evidence fo...
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Article
Open AccessChildren in reviews: Methodological issues in child-relevant evidence syntheses
The delivery of optimal medical care to children is dependent on the availability of child relevant research. Our objectives were to: i) systematically review and describe how children are handled in reviews o...
