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Article
Epidemiology of acute knee injuries seen at the Emergency Department at Umeå University Hospital, Sweden, during 15 years
To describe the incidence and injury distribution of knee injuries in the general population of a European setting.
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Article
Open AccessInhibitors of endopeptidase and angiotensin-converting enzyme lead to an amplification of the morphological changes and an upregulation of the substance P system in a muscle overuse model
We have previously observed, in studies on an experimental overuse model, that the tachykinin system may be involved in the processes of muscle inflammation (myositis) and other muscle tissue alterations. To f...
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Article
VGluT2 and NMDAR1 Expression in Cells in the Inflammatory Infiltrates in Experimentally Induced Myositis: Evidence of Local Glutamate Signaling Suggests Autocrine/Paracrine Effects in an Overuse Injury Model
It is not known whether a glutamate signaling system is involved in muscle inflammation (myositis). In the present study, we examined this question in the soleus muscle in a laboratory model of myositis result...
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Article
Do Both Areal BMD and Injurious Falls Explain the Higher Incidence of Fractures in Women than in Men?
The higher incidence of fractures in women than in men is generally attributed to the lower areal bone mineral density (areal BMD, g/cm2) of the former. The purpose of the present study was to investigate both ar...
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Article
Treatment of midportion Achilles tendinosis: similar clinical results with US and CD-guided surgery outside the tendon and sclerosing polidocanol injections
Sclerosing polidocanol injections targeting the area with vasculo/neural ingrowth on the ventral side of the tendon have previously been demonstrated to give good clinical results in patients with chronic pain...
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Article
Periosteal transplantation to the rabbit patella
Autologous periosteal transplantation (without chondrocyte cell transplantation) for treating traumatic articular cartilage defects of the patella gives pain relief in uncontrolled clinical studies. To study t...
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Article
Chronic Achilles tendon pain treated with eccentric calf-muscle training
Injuries involving the Achilles tendon and manifested as chronic tendon pain are common, especially among recreational athletes. In a pilot study on a small group of patients with chronic painful mid-portion A...
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Article
Intratendinous glutamate levels and eccentric training in chronic Achilles tendinosis: a prospective study using microdialysis technique
Microdialysis has shown intratendinous glutamate levels to be significantly higher in Achilles tendons with painful tendinosis than in normal pain-free tendons, and treatment with eccentric training has shown ...
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Article
Vitamin D receptor start codon polymorphism (FokI) is related to bone mineral density in healthy adolescent boys
Peak bone mass is considered a major determinant in the emergence of osteoporosis and is mainly genetically regulated. Several genes have been investigated, among them the vitamin D receptor (VDR) gene. A single...
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Article
Painful conditions in the Achilles tendon region: a common problem in middle-aged competitive badminton players
Overuse injuries are the most frequent type in badminton, generally localized in the legs. An earlier study found 32% of young Swedish elite badminton players to have experienced disabling pain in the Achilles...
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Article
Vitamin D receptor gene polymorphism is related to bone density, circulating osteocalcin, and parathyroid hormone in healthy adolescent girls
Bone mineral density (BMD) in adolescence is under strong genetic control and may influence the risk of future osteoporosis and resulting fracture. We investigated the vitamin D receptor (VDR) gene polymorphism...
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Article
Neovascularisation in Achilles tendons with painful tendinosis but not in normal tendons: an ultrasonographic investigation
Chronic Achilles tendinosis is a condition with unknown aetiology and pathogenesis, most often, but not always, associated with painful nodular thickening of the tendon. In this investigation, 28 tendons (21 p...
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Article
Glutamate NMDAR1 receptors localised to nerves in human Achilles tendons. Implications for treatment?
In this investigation, we show the presence of both free glutamate (microdialysis) and glutamate NMDAR1 receptors (immunohistochemical analyses of tendon biopsies), in tendons from patients with chronic Achill...
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Article
Chronic Achilles Tendinosis
Chronic Achilles tendinosis is a condition with an unknown aetiology and pathogenesis that is often, but not always, associated with pain during loading of the Achilles tendon. Histologically, there are no inf...
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Article
Superior results with continuous passive motion compared to active motion after periosteal transplantation A retrospective study of human patella cartilage defect treatment
Fifty-seven consecutive patients (33 men and 24 women), with a mean age of 32 years (range 16–53 years), who suffered from an isolated full-thickness cartilage defect of the patella and disabling knee pain of...
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Article
Treatment of tear of the anterior cruciate ligament combined with localised deep cartilage defects in the knee with ligament reconstruction and autologous periosteum transplantation
An acute tear of the anterior cruciate ligament (ACL) is frequently associated with injuries to the joint cartilage and subchondral bone. These injuries may progress to deep cartilage defects, causing disabli...
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Article
Treatment of deep cartilage defects of the patella with periosteal transplantation
Twenty-six consecutive patients (19 men and 7 women) with a mean age of 31.5 years (range 19–52 years) who suffered from an isolated full-thickness cartilage defect of the patella (area ranged from 0.75 to 20...
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Article
Does a torn anterior cruciate ligament lead to change in the central nervous drive of the knee extensors?
Integrated surface electromyograms of the three superficial parts of the quadriceps and isokinetic knee extensor maximum torque and power production were recorded simultaneously and at different angular veloci...
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Article
Relationship between work and electromyographic activity during repeated leg muscle contractions in orienteers
Contraction work (CW) was recorded for each of 200 repetitive isokinetic plantar flexions (1.05 rad · s−1) and knee extensions (1.57 rad · s−1) in 14 elite male orienteers. Simultaneous recordings of integrated e...
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Article
Quantitative morphological assessment of parathyroid activity in response to variations in calcium concentrationin vitro
Isolated parathyroid glands from gerbils incubated at low (0.5 mM), normal (1.25 mM) or high (3 mM) calcium concentration for 1 or 6 h were studied with regard to the following stereological parameters: the vo...
