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  1. Article

    Open Access

    Integrated genomic and transcriptomic analysis revealed mutation patterns of de-differentiated liposarcoma and leiomyosarcoma

    Treating patients with advanced sarcomas is challenging due to great histologic diversity among its subtypes. Leiomyosarcoma (LMS) and de-differentiated liposarcoma (DDLPS) are two common and aggressive subtyp...

    Wenshuai Liu, Hanxing Tong, Chenlu Zhang, Rongyuan Zhuang, He Guo, Chentao Lv… in BMC Cancer (2020)

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  2. Article

    Open Access

    Linc00423 as a tumor suppressor in retroperitoneal liposarcoma via activing MAPK signaling pathway through destabilizing of NFATC3

    Unraveling the noncoding RNA expression networks governing cancer initiation and development is essential while remains largely uncompleted in retroperitoneal liposarcoma (RLS). Through RNA-seq technologies an...

    Yong Zhang, Hanxing Tong, Junyi He, Yebo Shao, ** Guo… in Cell Death & Disease (2019)

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  3. No Access

    Article

    K-Ras mutation detection in liquid biopsy and tumor tissue as prognostic biomarker in patients with pancreatic cancer: a systematic review with meta-analysis

    K-Ras gene mutations have been found in most pancreatic cancers; however, conflicting data on the prognostic value of K-Ras mutations in pancreatic cancer have been published. We conducted a meta-analysis to a...

    Tao Li, Yuanting Zheng, Hong Sun, Rongyuan Zhuang, **g Liu… in Medical Oncology (2016)

  4. No Access

    Article

    Low-dosed docetaxel showed equivalent efficacy but improved tolerability compared with oxaliplatin in the S-1-based first-line chemotherapy regimen for metastatic or recurrent gastric adenocarcinoma

    Platinum–fluoropyrimidine combinations are the preferred first-line options for advanced gastric cancer (AGC) in East Asia. On the other hand, docetaxel-containing regimens without platinum have demonstrated p...

    Mengzhou Guo, Yiyi Yu, Yan Wang, Yuehong Cui, Qian Li, Yi Feng, Wei Li… in Medical Oncology (2015)