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177 Result(s)
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Article
Integrated Information for Pathogenicity and Treatment of Spiroplasma
Spiroplasma, belonging to the class Mollicutes, is a small, helical, motile bacterium lacking a cell wall. Its host range includes insects, plants, and aquatic crustaceans. Recently, a few human cases of Spiropla...
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Article
Open AccessGenome-wide identification of JAZ gene family members in autotetraploid cultivated alfalfa (Medicago sativa subsp. sativa) and expression analysis under salt stress
Jasmonate ZIM-domain (JAZ) proteins, which act as negative regulators in the jasmonic acid (JA) signalling pathway, have significant implications for plant development and response to abiotic stress.
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Harnessing key bacteria from suppressive soil to mitigate banana Panama disease
Soil microbiomes play a pivotal role in sha** plant health and their ability to suppress the pathogens. However, the specific microbial features that confer disease suppression in agricultural soils have rem...
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Article
The microbial metabolite agmatine acts as an FXR agonist to promote polycystic ovary syndrome in female mice
Polycystic ovary syndrome (PCOS), an endocrine disorder afflicting 6–20% of women of reproductive age globally, has been linked to alterations in the gut microbiome. We previously showed that in PCOS, elevatio...
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Article
Open AccessPotato yield and quality are linked to cover crop and soil microbiome, respectively
Crop-specific cultivation practices including crop rotation, cover crop**, and fertilisation are key measures for sustainable farming, for which soil microorganisms are important components. This study aims ...
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Article
Open AccessEfficacy and safety of mesenchymal stem cell therapy for ovarian ageing in a mouse model
Ovarian ageing is one of the major issues that impacts female fertility. Mesenchymal stem cell (MSC)-based therapy has made impressive progress in recent years. However, the efficacy and safety of MSCs, as non...
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Article
N1-methylpseudouridylation affects the fidelity of mRNA translation
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Protocol
Automated Real-Time Monitoring of Extracellular pH to Assess Early Plant Defense Signaling
Extracellular alkalinization mediated by the inhibition of plasma membrane-located proton pum** ATPases hallmarks the initiation of defense signaling in plant cells. Early defense responses also include depo...
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Protocol
Quantitative Measurement of Pattern-Triggered ROS Burst as an Early Immune Response in Tomato
The rapid accumulation of extracellular “reactive oxygen species” (ROS), also known as the “oxidative burst”, is an early plant immune response triggered by pathogen-derived microbe-associated molecular patter...
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Article
Open AccessIdentification, evolution, and expression of GDSL-type Esterase/Lipase (GELP) gene family in three cotton species: a bioinformatic analysis
GDSL esterase/lipases (GELPs) play important roles in plant growth, development, and response to biotic and abiotic stresses. Presently, an extensive and in-depth analysis of GELP family genes in cotton is still ...
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Article
Wireless multisite physiological sensor with clinical-grade accuracy
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Article
Classification of Glomerular Pathology Images in Children Using Convolutional Neural Networks with Improved SE-ResNet Module
Classification of glomerular pathology based on histology sections is the key to diagnose the type and degree of kidney diseases. To address problems in the classification of glomerular lesions in children, a ...
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Article
Morphological and Pull-Out Mechanical Properties of Alfalfa Roots in the Seedling Stage
The mechanical properties of plant roots in the early growth stage are not clear, which limits the application of plants in soil reinforcement and slope protection. Thus, this study tried to understand the str...
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Article
Open AccessRegulating bulb dormancy release and flowering in lily through chemical modulation of intercellular communication
Lily is a bulbous plant with an endogenous dormancy trait. Fine-tuning bulb dormancy release is still a challenge in the development of bulb storage technology. In this study, we identified three regulators of...
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Article
Open AccessSynergistic antitumor efficacy of aspirin plus lenvatinib in hepatocellular carcinoma via regulating of diverse signaling pathways
It has been established that monotherapy yields limited efficacy in treating hepatocellular carcinoma (HCC), especially advanced HCC. Increasing evidence from preclinical studies and clinical trials indicates ...
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Article
Precise intraoperative brain tumor classification
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Article
Advancing missense variant pathogenicity prediction
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Article
Characterization of the fragmented mitochondrial genome of domestic pig louse Haematopinus suis (Insecta: Haematopinidae) from China
The domestic pig louse Haematopinus suis (Linnaeus, 1758) (Phthiraptera: Anoplura) is a common ectoparasite of domestic pigs, which can act as a vector of various infectious disease agents. Despite its significan...
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Article
Open AccessTomato growth stage modulates bacterial communities across different soil aggregate sizes and disease levels
Soil aggregates contain distinct physio-chemical properties across different size classes. These differences in micro-habitats support varied microbial communities and modulate the effect of plant on microbiom...
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Article
KDM6A epigenetically regulates subtype plasticity in small cell lung cancer
Small cell lung cancer (SCLC) exists broadly in four molecular subtypes: ASCL1, NEUROD1, POU2F3 and Inflammatory. Initially, SCLC subtypes were thought to be mutually exclusive, but recent evidence shows intra...