17 Result(s)

Article

Tracking donor RBC survival in premature infants: agreement of multiple populations of biotin-labeled RBCs with Kidd antigen–mismatched RBCs

Anemia, a common condition among critically ill premature infants, is affected by red blood cell (RBC) survival (RCS). We hypothesized that transfused allogeneic Kidd antigen–mismatched RBCs would demonstrate ...

John A. Widness, Demet Nalbant, Nell I. Matthews, Ronald G. Strauss… in Pediatric Research (2013)

Article

Comparison of multiple red cell volume methods performed concurrently in premature infants following allogeneic transfusion

Study of the pathophysiology and treatment of anemia of prematurity is facilitated by direct measurement of red cell volume (RCV) utilizing microliter quantities of blood samples. Our objective was to compare ...

Demet Nalbant, Prasad Bhandary, Nell I. Matthews, Robert L. Schmidt… in Pediatric Research (2013)

Article

Red Cell Volume Can Be Accurately Determined in Sheep Using a Nonradioactive Biotin Label

The sheep has served as an informative animal model for investigation of human fetal and newborn erythropoiesis and red blood cell (RBC) kinetics. We previously validated the permanent label (¹⁴C)cyanate for meas...

Donald M Mock, Nell I Mock, Gary L Lankford, Leon F Burmeister… in Pediatric Research (2008)

Article

Circulating Red Cell Volume and Red Cell Survival Can Be Accurately Determined in Sheep Using the [¹⁴C]Cyanate Label

The sheep commonly serves as an animal model for investigation of human fetal and newborn erythropoiesis and red blood cell kinetics. Measurement of red cell volume (RCV) and survival (RCS) in sheep would be u...

Donald M Mock, Gary L Lankford, Leon F Burmeister, Ronald G Strauss in Pediatric Research (1997)

Article

[¹⁴C]Cyanate Labeling of Sheep Red Cells: Covalent Binding to Hemoglobin Continues in Vivo for a Day

The sheep is a useful model to study fetal and newborn physiology including perinatal erythropoiesis and red cell kinetics. A practical, economical method for measuring red cell survival (RCS) in sheep would b...

Donald M Mock, Ronald G Strauss, Gary L Lankford in Pediatric Research (1997)

Article

CHANGING PATTERNS OF RED BLOOD CELL TRANSFUSION IN VERY LOW BIRTHWEIGHT INFANTS. † 1500

John A Widness, Victoria J Seward, Irma J Kromer, Leon F Burmeister… in Pediatric Research (1996)

Article

1537 UNIT DOSE, READY-TO-USE BLOOD PRODUCTS FOR NEONATES

A system was designed to dispense precise volumes of prefiltered, sterile, quality blood for immediate infusion into designated infants without waste. In the blood bank, the volume ordered was aspirated from t...

Ronald G Strauss, Char Elbert, Greta Crawford, Esther L Snyder… in Pediatric Research (1985)

Article

UPTAKE OF RADIOACTIVE CALCIUM (⁴⁵Ca) BY NEUTROPHILS (PMN) FROM HUMAN NEONATES

Abnormal chemotaxis, deformability, and lectin cap** of neonatal PMN may be due to abnormal plasma membrane structure or function (eg, altered Ca uptake after pertubation). We studied ⁴⁵Ca uptake by blood PMN f...

Ronald G Strauss, Esther L Snyder in Pediatric Research (1984)

Article

Activation and Activity of the Superoxide-Generating System of Neutophils from Human Infants

Summary: We investigated the superoxide-generating system of neutrophils obtained from human neonates and their mothers. Using a standard assay to measure the cumulative production of superoxide anion over 15 ...

Ronald G Strauss, Esther L Snyder in Pediatric Research (1983)

Article

Spontaneous and Drug-Induced Concanavalin A Cap** of Neutrophils from Human Infants and Their Mothers

Summary: We investigated concanavalin A cap** that occurred either spontaneously (neutrophils incubated only with buffer) or was drug induced (neutrophils with colchicine or diamide) using neutrophils obtain...

Ronald G Strauss, Michael J Hart in Pediatric Research (1981)

Article

880 AUTOOXIDATION AND DECREASED VIABILITY OF NEUTROPHILS OBTAINED FROM HUMAN INFANTS

Infant neutrophils (N) exhibit decreased viability in vitro. We investigated autooxidation as a cause since increased oxidative metabolism and decreased oxidant protective enzymes (glutathione peroxidase and c...

Ronald G Strauss, Esther L Snyder in Pediatric Research (1981)

Article

879 ABNORMAL CONCANAVALIN A CAPPING – ANOTHER DEFECT OF NEUTROPHILS FROM HUMAN INFANTS

Concanavalin A (con A) binds to neutrophil (N) plasma membranes and induces granule exocytosis, chemotaxis and increased oxidative metabolism. Con A binds diffusely to the N surface, but caps form on N exposed...

Ronald G Strauss, Michael J Hart in Pediatric Research (1981)

Article

OXIDATIVE METABOLISM IN HUMAN CORD BLOOD NEUTROPHILS

Oxidative metabolism (OxM) was assessed in cord blood, neutrophils (CBN) in an attempt to explain the susceptibility of infants to infections. A variety of methods were employed in prior reports, and results h...

Ronald G Strauss, M J Seifert in Pediatric Research (1977)

Article

Alternative Pathway of Complement in Sickle Cell Disease

Summary: Thirty-one patients, 10 months to 20 years of age, were studied. A complement abnormality was not identified in sera from patients with sickle cell disease (SCD) by the methods employed in the present...

Ronald G Strauss, Theresa Asbrock, Judith Forristal, Clark D West in Pediatric Research (1977)

Article

VARICELLA-ZOSTER VIREMIA: ASSOCIATION WITH PROGRESSIVE VARICELLA

In retrospect, progressive varicella (the clinical involvement of organ systems other than the skin, the prolonged appearance of vesicles, or clinically significant hemorrhage) is usually not difficult to dist...

Martin G Myers, Ronald G Strauss in Pediatric Research (1977)