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    Article

    Sjögren syndrome

    Sjögren syndrome (SjS) is a systemic autoimmune disease that primarily affects the exocrine glands (mainly the salivary and lacrimal glands) and results in the severe dryness of mucosal surfaces, principally i...

    Pilar Brito-Zerón, Chiara Baldini, Hendrika Bootsma in Nature Reviews Disease Primers (2016)

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    Open Access

    The neutrophil protein S100A12 is associated with a comprehensive ultrasonographic synovitis score in a longitudinal study of patients with rheumatoid arthritis treated with adalimumab

    The calcium-binding protein S100A12 correlates with measures of disease activity in patients with rheumatoid arthritis (RA). The protein reflects neutrophil activation and the present objective was to explore ...

    Hilde Haugedal Nordal, Johan G Brun, Anne-Kristine Halse in BMC Musculoskeletal Disorders (2014)

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    Chapter

    Histopathology and Glandular Biopsies in Sjögren’s Syndrome

    The glandular inflammatory lesion in Sjögren’s syndrome (SS) is a distinctive but not pathognomonic chronic lymphocytic adenitis best characterized in salivary glands. The glands are readily accessible; decrea...

    Roland Jonsson, Kathrine Skarstein, Malin V. Jonsson in Sjögren’s Syndrome (2012)

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    Chapter

    Etiology and Pathogenesis of Sjögren’s Syndrome with Special Emphasis on the Salivary Glands

    Pathogenesis from the Greek pathos, “disease,” and genesis, “creation,” is the process by which an etiological factor and subsequent downstream events cause disease. Although in Sjögren’s syndrome (SS), alike ...

    Nicolas Delaleu, Menelaos N. Manoussakis, Haralampos M. Moutsopoulos in Sjögren’s Syndrome (2012)

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    Oral and Dental Manifestations of Sjögren’s Syndrome: Current Approaches to Diagnostics and Therapy

    Saliva plays a detrimental role in oral health and disease. The quality and the quantity of saliva are determined by the glands it is secreted from, the sampling method, and whether secretion is stimulated or ...

    Malin V. Jonsson, Nicolas Delaleu, Mihaela C. Marthinussen in Sjögren’s Syndrome (2012)

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    Article

    Animal Models of Sjögren’s Syndrome

    Sjögren’s syndrome is an autoimmune, chronic inflammatory disease characterized by focal mononuclear cell infiltration of exocrine tissues, accompanied by loss of secretory function. The pathogenesis of autoim...

    Malin V. Jonsson, Nicolas Delaleu in Clinical Reviews in Allergy & Immunology (2007)