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Article
Controlled Comparison of Simulated Hemodynamics Across Tricuspid and Bicuspid Aortic Valves
Bicuspid aortic valve is the most common congenital heart defect, affecting 1–2% of the global population. Patients with bicuspid valves frequently develop dilation and aneurysms of the ascending aorta. Both h...
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Article
A design-based model of the aortic valve for fluid-structure interaction
This paper presents a new method for modeling the mechanics of the aortic valve and simulates its interaction with blood. As much as possible, the model construction is based on first principles, but such that...
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Article
Designing clinically translatable artificial intelligence systems for high-dimensional medical imaging
The National Institutes of Health in 2018 identified key focus areas for the future of artificial intelligence in medical imaging, creating a foundational roadmap for research in image acquisition, algorithms,...
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Article
Open AccessPredicting post-operative right ventricular failure using video-based deep learning
Despite progressive improvements over the decades, the rich temporally resolved data in an echocardiogram remain underutilized. Human assessments reduce the complex patterns of cardiac wall motion, to a small ...
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Chapter and Conference Paper
Cardiac Support for the Right Ventricle: Effects of Timing on Hemodynamics-Biomechanics Tradeoff
A well-established treatment option for advanced heart failure is the implantation of a ventricular assist device (VAD) in the left heart. In over one quarter of patients, however, failure of the right ventric...
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Article
MDCT-based lung volumetry as a prognostic tool—miles to go before we sleep
