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Article
Open AccessCorrelates and trajectories of relapses in relapsing–remitting multiple sclerosis
In people with relapsing–remitting multiple sclerosis (pwRRMS), data from studies on non-pharmacological factors which may influence relapse risk, other than age, are inconsistent. There is a reduced risk of r...
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Article
Open AccessMeasuring disability in multiple sclerosis: the WHODAS 2.0
Reliable measurement of disability in multiple sclerosis (MS) using a comprehensive, patient self-reported scale, such as the World Health Organization Disability Assessment Schedule (WHODAS) 2.0, would be of ...
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Article
Open AccessGerman translation, cultural adaptation and validation of the unidimensional self-efficacy scale for multiple sclerosis
Self-efficacy concerns individuals’ beliefs in their capability to exercise control in specific situations and complete tasks successfully. In people with multiple sclerosis (PwMS), self-efficacy has been asso...
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Article
Open AccessUrgent referral for suspected CNS cancer: which clinical features are associated with a positive predictive value of 3 % or more?
Urgent referral for suspected central nervous system (CNS) cancer is recommended, but little analysis of the referral criteria diagnostic performance has been conducted. New 2015 NICE guidance recommends direc...
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Article
Open AccessValidation of the Neurological Fatigue Index for stroke (NFI-Stroke)
Fatigue is a common symptom in Stroke. Several self-report scales are available to measure this debilitating symptom but concern has been expressed about their construct validity.
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Article
Open AccessDevelopment of a patient reported outcome measure for fatigue in motor neurone disease: the Neurological Fatigue Index (NFI-MND)
The objective of this research was to develop a disease-specific measure for fatigue in patients with motor neurone disease (MND) by generating data that would fit the Rasch measurement model. Fatigue was defi...
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Article
Open AccessRasch analysis of the Hospital Anxiety and Depression Scale (HADS) for use in motor neurone disease
The Hospital Anxiety and Depression Scale (HADS) is commonly used to assess symptoms of anxiety and depression in motor neurone disease (MND). The measure has never been specifically validated for use within t...
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Article
Open AccessDevelopment of a patient reported outcome scale for fatigue in multiple sclerosis: The Neurological Fatigue Index (NFI-MS)
Fatigue is a common and debilitating symptom in multiple sclerosis (MS). Best-practice guidelines suggest that health services should repeatedly assess fatigue in persons with MS. Several fatigue scales are av...
