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  1. No Access

    Article

    Hyaluronidase ameliorates rejection-induced edema

    Hyaluronan, a glucosaminoglycan with unique water-binding capacity, is accumulated in the interstitial edematous tissue in rejecting organs. We here investigated whether the increased tissue content of water ...

    C. Johnsson, Roger Hällgren, Anders Elvin, Bengt Gerdin… in Transplant International (1999)

  2. No Access

    Article

    Regional Rectal Perfusion: A New in Vivo Approach to Study Rectal Drug Absorption in Man

    Background: In vivo permeability measurements of drugs in the colonic/rectal region in humans are difficult. A new instrument for the perfusion of a defined and closed segment in the colon/rectum was developed...

    Hans Lennernäs, Urban Fagerholm, Yngve. Raab, Bengt Gerdin… in Pharmaceutical Research (1995)

  3. Article

    205 HYALURONAN AND WATER CONTENT IN THE LUNG OF PRETERM AND TERM INFANTS WHO DIED LESS THAN 24 HOURS AFTER BIRTH

    Fetal connective tissue is known to have a very high concentration of hyaluronan (HA) and of water. In rabbit pups the concentration of HA in the lung has its lowest value one day before term gestation (Am J P...

    Gunnar Sedin, Bengt Gerdin, Hans Johnsson, Anders Jonzon… in Pediatric Research (1994)

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  4. No Access

    Article

    Regional Jejunal Perfusion, a New in Vivo Approach to Study Oral Drug Absorption in Man

    Recently a new in vivo approach in man, using a regional intestinal perfusion technique, has been developed. The perfusion tube consists of a multichannel tube with two inflatable balloons, which are placed 10 cm...

    Hans Lennernäs, Örjan Ahrenstedt, Roger Hällgren, Lars Knutson… in Pharmaceutical Research (1992)

  5. No Access

    Article

    Jejunal secretion of secretory immunoglobulins and gliadin antibodies in celiac disease

    The aim of this study was to determine the secretion of secretory immunoglobulins and gliadin antibodies in the small bowel in celiac disease. Twenty-four patients were investigated by perfusion of a defined j...

    Dr. Bengt Lavö, Folke Knutson, Lars Knutson… in Digestive Diseases and Sciences (1992)

  6. No Access

    Article

    Metal content of neutrophil granules is altered in chronic inflammation

    The mass fraction of certain elements was measured in isolated granulocytes and isolated granulocyte granule fractions from patients with active inflammatory arthritides (N=6) and healthy controls (N=6). The pati...

    Roger Hällgren, Nils Feltelius, Rodolfo Garcia, Per Venge, Ulf Lindh in Inflammation (1989)

  7. No Access

    Chapter and Conference Paper

    Clinical Effects and Renal Side Effects in Patients with Autoimmune Diseases Treated with Ciclosporin (CyA)

    We have used ciclosporin (CyA) since 1981 in the treatment of selected cases with severe autoimmune diseases. Our first patient suffered from life-threatening relapsing polychondritis. She had been treated wit...

    Karin Svenson MD, Sven-Olof Bohman, Roger Hällgren in Ciclosporin in Autoimmune Diseases (1985)

  8. No Access

    Chapter

    The Effect of Hyaluronic Acid on Neutrophil Function in Vitro and in Vivo

    Defective neutrophil function is an established cause of increased infection propensity. In addition defects may also predispose to other diseases such as SLE (to be published) and reumatoid arthritis1 due to an ...

    Per Venge, Lena Håkansson, Roger Hällgren… in Biochemistry and Function of Phagocytes (1982)