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  1. Article

    Open Access

    Remission from antipsychotic treatment in first episode psychosis related to longitudinal changes in brain glutamate

    Neuroimaging studies in schizophrenia have linked elevated glutamate metabolite levels to non-remission following antipsychotic treatment, and also indicate that antipsychotics can reduce glutamate metabolite ...

    Kate Merritt, Rocio Perez-Iglesias, Kyra-Verena Sendt, Rhianna Goozee in npj Schizophrenia (2019)

  2. No Access

    Article

    Long-term metabolic effects of aripiprazole, ziprasidone and quetiapine: a pragmatic clinical trial in drug-naïve patients with a first-episode of non-affective psychosis

    The use of second-generation antipsychotics (SGA) has been associated with metabolic changes. However, there are differences in the metabolic profile between SGAs. We have previously observed that ziprasidone ...

    Javier Vázquez-Bourgon, Rocío Pérez-Iglesias in Psychopharmacology (2018)

  3. No Access

    Article

    Common genetic variants influence human subcortical brain structures

    Genome-wide association studies are used to identify common genetic variants that affect the structure of selected subcortical regions of the human brain; their identification provides insight into the causes ...

    Derrek P. Hibar, Jason L. Stein, Miguel E. Renteria, Alejandro Arias-Vasquez in Nature (2015)

  4. Article

    Treatment of first-episode non-affective psychosis: a randomized comparison of aripiprazole, quetiapine and ziprasidone over 1 year

    Discontinuation of antipsychotic treatment at early phases increases the risk of poor adherence to maintenance drug therapy. Differences among antipsychotics in terms of effectiveness may determine a good adhe...

    Benedicto Crespo-Facorro, Victor Ortiz-Garcia de la Foz, Ignacio Mata in Psychopharmacology (2014)

  5. Article

    Long-term (3-year) neurocognitive effectiveness of antipsychotic medications in first-episode non-affective psychosis: a randomized comparison of haloperidol, olanzapine, and risperidone

    The initially postulated superior neurocognitive effectiveness of second-generation antipsychotics is currently under debate.

    Rosa Ayesa-Arriola, Jose Manuel Rodríguez-Sánchez in Psychopharmacology (2013)

  6. No Access

    Article

    Homocysteine and cognition in first-episode psychosis patients

    In the last years, there has been growing evidence linking elevated homocysteine levels with cognitive dysfunction in several neurological and neuropsychiatric diseases. The aim of the present study was to inv...

    Rosa Ayesa-Arriola, Rocío Pérez-Iglesias in European Archives of Psychiatry and Clinic… (2012)

  7. No Access

    Article

    Long-term (3-year) effectiveness of haloperidol, risperidone and olanzapine: results of a randomized, flexible-dose, open-label comparison in first-episode nonaffective psychosis

    To enhance the effectiveness of antipsychotics in first-episode psychosis is crucial in order to achieve the most favourable prognosis. Difference in effectiveness between antipsychotics is still under debate.

    Benedicto Crespo-Facorro, Rocío Pérez-Iglesias, Ignacio Mata in Psychopharmacology (2012)

  8. No Access

    Article

    Antipsychotic-Induced Weight Gain in Chronic and First-Episode Psychotic Disorders

    Antipsychotic-induced weight gain is an important issue in the treatment of psychotic illnesses, and affects 80% of individuals being treated with antipsychotic drugs. However, the true dimension of weight gai...

    Dr Mario Álvarez-Jiménez, César González-Blanch, Benedicto Crespo-Facorro in CNS Drugs (2008)

  9. No Access

    Article

    Cognitive functioning and negative symptoms in first episode schizophrenia: Different patterns of correlates

    Negative symptoms of schizophrenia have been related to disturbances of executive functions, memory, attention and motor functioning. The executive functions dimension comprises a variety of cognitive subproce...

    JosÉ Manuel RodrÍguez-SÁnchez, Benedicto Crespo-Facorro in Neurotoxicity Research (2008)

  10. Article

    Open Access

    Smoking among pregnant women in Cantabria (Spain): trend and determinants of smoking cessation

    Cantabria (Spain) has one of the highest prevalence of smoking among women of the European Union. The objectives are to assess the trend of smoking during pregnancy in a five-year period and the determinants o...

    Silvia Palma, Rocio Pérez-Iglesias, Rosa Pardo-Crespo, Javier Llorca in BMC Public Health (2007)

  11. No Access

    Article

    Cognitive functioning in the early course of first-episode schizophrenia spectrum disorders

    The aim of this study was to examine possible cognitive changes throughout the early course of schizophrenia spectrum disorders.

    César González-Blanch, Mario Álvarez-Jiménez in European Archives of Psychiatry and Clinic… (2006)