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  1. Article

    Open Access

    Correction to: Patients’ usability of seven most used dry-powder inhalers in COPD

    After publication of the Original research article [1] it was brought to our attention that the sentence at the bottom of the section entitled Discussion (pag 6 of 9, just below Fig. 4) must be corrected as fo...

    Roberto W. Dal Negro, Paola Turco in Multidisciplinary Respiratory Medicine (2019)

  2. Article

    Open Access

    Patients’ usability of seven most used dry-powder inhalers in COPD

    Inhalation devices affect both the effectiveness and the therapeutic outcomes in persistent airway obstruction, and the effects are largely independent of the drug(s) assumed. Usability is a complex and compre...

    Roberto W. Dal Negro, Paola Turco in Multidisciplinary Respiratory Medicine (2019)

  3. Article

    Open Access

    Acute cough in Italian children: parents’ beliefs, approach to treatment, and the family impact

    Acute cough is the most common symptom among children in primary care, but the impact of cough episodes was never investigated in Italian families.

    Roberto W. Dal Negro, Alessandro Zanasi in Multidisciplinary Respiratory Medicine (2019)

  4. Article

    Open Access

    Correction to: Fluticasone furoate/Vilanterol 92/22 μg once-a-day vs Beclomethasone dipropionate/Formoterol 100/6 μg b.I.D.: a 12-month comparison of outcomes in mild-to-moderate asthma

    After publication of the Original research article [1] it was brought to our attention that the sentence at pag 6 (between Figure 3 and Figure 4)) must be corrected as follows: “The mean duration of inactivity...

    Roberto W. Dal Negro, Luca Bonadiman, Paola Turco in Multidisciplinary Respiratory Medicine (2018)

  5. Article

    Open Access

    XII AIST 2018 Conference: “The thousand faces of cough: clinical and therapeutic updates”

    This paper summarizes the presentations submitted for publication of the 12th AIST National Congress (Associazione Italiana Studio Tosse/Italian Association for Cough Study) entitled “The thousand facets of cough...

    Alessandro Zanasi, Antonio M. Morselli-Labate in Multidisciplinary Respiratory Medicine (2018)

  6. Article

    Open Access

    Fluticasone furoate/Vilanterol 92/22 μg once-a-day vs Beclomethasone dipropionate/Formoterol 100/6 μg b.I.D.: a 12-month comparison of outcomes in mild-to-moderate asthma

    Bronchial asthma is an inflammatory disease of the airways. Beclomethasone dipropionate/Formoterol (BDP/F) and Fluticasone furoate/Vilanterol (FF/V) are two of the most effective LABA/ICS combinations for mana...

    Roberto W. Dal Negro, Luca Bonadiman, Paola Turco in Multidisciplinary Respiratory Medicine (2018)

  7. Article

    Open Access

    Influenza and influenza-like syndromes: the subjects’ beliefs, the attitude to prevention and treatment, and the impact in Italian general population

    Influenza and influenza-like syndromes (I-LSs) are infectious diseases occurring on a seasonal basis which can lead to upper (URTI) and lower respiratory tract illness (LRTI) of different severity. The approac...

    Roberto W. Dal Negro, Alessandro Zanasi in Multidisciplinary Respiratory Medicine (2018)

  8. No Access

    Chapter

    COPD: Economical and Surrogate Outcomes—The Case of COPD

    We will discuss the overall economics in pulmonary rehabilitation by taking chronic obstructive pulmonary disease (COPD) as a model because it is the most prevalent and incident chronic respiratory pathology [...

    Roberto W. Dal Negro, Claudio F. Donner in Textbook of Pulmonary Rehabilitation (2018)

  9. Article

    Open Access

    Instant velocity and consistency of emitted cloud change by the different levels of canister filling with Metered Dose Inhalers (MDIs), but not with Soft Mist Inhalers (SMIs): a bench study

    Inhalation is the preferred route for respiratory drug delivery, but several factors contribute to the variability of the respirable dose fraction. Instant velocity and the dynamic characteristics of the dropl...

    Roberto W. Dal Negro, Pietro Longo in Multidisciplinary Respiratory Medicine (2017)

  10. Article

    Open Access

    Cost of persistent asthma in Italy

    Asthma is a common disease of the airways with a significant burden for the society and for patients’ quality of life. The Social Impact of Respiratory Integrated Outcomes (SIRIO) study estimated a mean cost o...

    Roberto W. Dal Negro, Chiara Distante in Multidisciplinary Respiratory Medicine (2016)

  11. Article

    Open Access

    Cough: impact, beliefs, and expectations from a national survey

    Cough is one of the most common discomforts affecting general population, which can disrupt subjects’ quality of life due to its physical, social, and psychological effects. Aim of the study was to investigate...

    Roberto W. Dal Negro, Massimiliano Mazzolini in Multidisciplinary Respiratory Medicine (2016)

  12. Article

    Open Access

    Dry-powder inhalers in patients with persistent airflow limitation: usability and preference

    Inhalation devices represent per sé critical factors because they can affect the therapeutic outcomes independently of the drug used. The role of patients’ usability and preference (PUP) for Dry Powder Inhalers (...

    Roberto W. Dal Negro, Massimiliano Povero in Multidisciplinary Respiratory Medicine (2016)

  13. Article

    Open Access

    Cultural and linguistic validation of the NHQ-2 Questionnaire: a specific instrument for assessing patient’s usability of inhalation devices

    An increasing number of inhalation devices are presently available in the market. They are differently characterized in terms of their handling and usability, both factors which may affect the outcomes of resp...

    Roberto W. Dal Negro, Massimiliano Povero in Multidisciplinary Respiratory Medicine (2016)

  14. Article

    Open Access

    Fluticasone furoate/Vilanterol 92/22 μg once-a-day vs Beclomethasone dipropionate/ Formoterol 100/6 μg b.i.d.: a 12-week cost analysis in mild-to-moderate asthma

    Asthma is a disease with high cost for the National Health Service. Two of the most recent LABA/ICS combinations for persistent bronchial asthma are Beclomethasone dipropionate/Formoterol (B/F) delivered via t...

    Roberto W. Dal Negro, Chiara Distante in Multidisciplinary Respiratory Medicine (2016)

  15. Article

    Open Access

    The BODECOST Index (BCI): a composite index for assessing the impact of COPD in real life

    Chronic Obstructive Pulmonary Disease (COPD) is a progressive condition which is characterized by a dramatic socio-economic impact.

    Roberto W. Dal Negro, Bartolome R. Celli in Multidisciplinary Respiratory Medicine (2016)

  16. Article

    Open Access

    Acceptability and preference of three inhalation devices assessed by the Handling Questionnaire in asthma and COPD patients

    The patients’ criteria of preference for inhalation devices can affect the extent of their adherence to treatment and outcomes.

    Roberto W. Dal Negro, Massimiliano Povero in Multidisciplinary Respiratory Medicine (2016)

  17. Article

    Open Access

    Cognitive dysfunction in severe chronic obstructive pulmonary disease (COPD) with or without Long-Term Oxygen Therapy (LTOT)

    Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory condition which can lead to comorbidities of variable severity, cognitive dysfunction included. The role of supplemental oxygen in prev...

    Roberto W Dal Negro, Luca Bonadiman in Multidisciplinary Respiratory Medicine (2015)

  18. Article

    Open Access

    Dry powder inhalers and the right things to remember: a concept review

    Dry powder inhalers (DPIs) are widely and increasingly used in clinical practice because they represent a substantial advancement in inhalation technology. The effectiveness of a powdered drug to inhale depend...

    Roberto W Dal Negro in Multidisciplinary Respiratory Medicine (2015)

  19. Article

    Open Access

    Sensitivity of the COPD assessment test (CAT questionnaire) investigated in a population of 681 consecutive patients referring to a lung clinic: the first Italian specific study

    Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality at global level even if still underestimated. The insufficient use of specific tools for an objective definition and sta...

    Roberto W Dal Negro, Luca Bonadiman, Paola Turco in Multidisciplinary Respiratory Medicine (2014)

  20. Article

    Poster 1002: Galectin-3 as predictive biomarker of airways remodeling modulation in omalizumab treated severe asthma patients

    Pierluigi Mauri, Annamaria Riccio, Rossana Rossi in World Allergy Organization Journal (2014)

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