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Article

SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability

Innervation of the hypothalamic median eminence by Gonadotropin-Releasing Hormone (GnRH) neurons is vital to ensure puberty onset and successful reproduction. However, the molecular and cellular mechanisms und...

Antonella Lettieri, Roberto Oleari, Marleen Hester van den Munkhof… in Nature Communications (2023)