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Article
Open AccessNeuronal activation sequences in lateral prefrontal cortex encode visuospatial working memory during virtual navigation
Working memory (WM) is the ability to maintain and manipulate information ‘in mind’. The neural codes underlying WM have been a matter of debate. We simultaneously recorded the activity of hundreds of neurons ...
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Article
Open AccessPrimacy of vision shapes behavioral strategies and neural substrates of spatial navigation in marmoset hippocampus
The role of the hippocampus in spatial navigation has been primarily studied in nocturnal mammals, such as rats, that lack many adaptations for daylight vision. Here we demonstrate that during 3D navigation, t...
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Article
Open AccessKetamine disrupts naturalistic coding of working memory in primate lateral prefrontal cortex networks
Ketamine is a dissociative anesthetic drug, which has more recently emerged as a rapid-acting antidepressant. When acutely administered at subanesthetic doses, ketamine causes cognitive deficits like those obs...
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Article
The application of noninvasive, restraint-free eye-tracking methods for use with nonhuman primates
Over the past 50 years there has been a strong interest in applying eye-tracking techniques to study a myriad of questions related to human and nonhuman primate psychological processes. Eye movements and fixat...
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Article
Context-dependent representations of objects and space in the primate hippocampus during virtual navigation
The hippocampus is implicated in associative memory and spatial navigation. To investigate how these functions are mixed in the hippocampus, we recorded from single hippocampal neurons in macaque monkeys navig...
