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Article
Open AccessNear-Infrared Spectroscopy measurements are reliable for studying patellar bone hemodynamics and affected by venous occlusion, but not by skin compression
According to the homeostasis model, patellofemoral pain (PFP) results from disturbed homeostasis due to vascular insufficiency in the anterior knee. Near-Infrared Spectroscopy (NIRS) measures relative changes ...
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Article
Open AccessCharacterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium
Biomarkers predictive of inflammatory events post-vaccination could accelerate vaccine development. Within the BIOVACSAFE framework, we conducted three identically designed, placebo-controlled inpatient/outpat...
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Article
Open AccessAxonal transport deficits in multiple sclerosis: spiraling into the abyss
The transport of mitochondria and other cellular components along the axonal microtubule cytoskeleton plays an essential role in neuronal survival. Defects in this system have been linked to a large number of ...
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Article
Open AccessResolving bundled microtubules using anti-tubulin nanobodies
Microtubules are hollow biopolymers of 25-nm diameter and are key constituents of the cytoskeleton. In neurons, microtubules are organized differently between axons and dendrites, but their precise organizatio...
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Article
Correction: Corrigendum: A role for Bicaudal-D2 in radial cerebellar granule cell migration
Nature Communications 5: Article number: 3411 (2014); Published: 11 March 2014; Updated: 7 July 2014. The affiliation details for Susan van Erp are incorrect in this Article. The correct affiliation details fo...
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Article
A role for Bicaudal-D2 in radial cerebellar granule cell migration
Bicaudal-D (BICD) belongs to an evolutionary conserved family of dynein adaptor proteins. It was first described in Drosophila as an essential factor in fly oogenesis and embryogenesis. Missense mutations in a hu...
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Molecular Motors in Cargo Trafficking and Synapse Assembly
Every production process, be it cellular or industrial, depends on a constant supply of energy and resources. Synapses, specialized junctions in the central nervous system through which neurons signal to each ...