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Article
Biomarkers of platelet activation and cardiovascular risk in the DAPT trial
Prolonged use of dual antiplatelet therapy (DAPT) post-percutaneous coronary intervention (PCI) has been shown to reduce the risk of major adverse cardiovascular events (MACE), but with increased bleeding. It ...
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Article
Open AccessTrends and predictors of early ablation for Atrial Fibrillation in a Nationwide population under age 65: a retrospective observational study
Catheter ablation (CA) has emerged as an effective treatment for symptomatic atrial fibrillation (AF). However practice patterns and patient factors associated with referral for CA within the first 12 months a...
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Article
High-Risk Percutaneous Coronary Intervention in Public Reporting States: the Evidence, Exclusion of Critically Ill Patients, and Implications
Public reporting of outcomes for percutaneous coronary intervention (PCI) is used in some states to drive improvements in care delivery and performance. However, a growing body of evidence suggests unintended ...
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Article
Real-time fusion of coronary CT angiography with x-ray fluoroscopy during chronic total occlusion PCI
The purpose of this study was to demonstrate the feasibility of real-time fusion of coronary computed tomography angiography (CTA) centreline and arterial wall calcification with x-ray fluoroscopy during chron...
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Article
New-Generation Coronary Stents: Current Data and Future Directions
Drug-eluting stents are the mainstay in the treatment of coronary artery disease using percutaneous coronary intervention. Innovations developed to overcome the limitations of prior generations of stents inclu...
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Article
Dual Antiplatelet Therapy in Patients with Stable Ischemic Heart Disease
Dual antiplatelet therapy (DAPT) is the use of a P2Y12 receptor antagonist (clopidogrel, prasugrel, or ticagrelor) in combination with aspirin. Recommendations for its use are primarily in patients who have ex...
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Article
Public Reporting of PCI Outcomes: For Better or for Worse
Public reporting of PCI outcomes has had a polarizing effect on the cardiology community. The potential benefits of public reporting are many, but a host of unintended consequences have likely mitigated the an...
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Article
Open AccessAccounting for the mortality benefit of drug-eluting stents in percutaneous coronary intervention: a comparison of methods in a retrospective cohort study
Drug-eluting stents (DES) reduce rates of restenosis compared with bare metal stents (BMS). A number of observational studies have also found lower rates of mortality and non-fatal myocardial infarction with D...
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Article
Safety and efficacy of the argatroban therapy during the early post-cardiac surgery period
Heparin-induced thrombocytopenia (HIT) is associated with a high incidence of vein graft occlusion after cardiac surgery. When HIT is suspected during the post-operative period, current guideline recommends a ...
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Article
Efficacy and safety of argatroban with or without glycoprotein IIb/IIIa inhibitor in patients with heparin induced thrombocytopenia undergoing percutaneous coronary intervention for acute coronary syndrome
There is limited experience with the use of argatroban in combination with glycoprotein IIb/IIIa (GPIIb/IIIa) inhibitor in acute coronary syndrome (ACS) patients with heparin-induced thrombocytopenia (HIT) und...
