5 Result(s)
within
Robert Ekblom
Animal Genetics and Genomics
Life Sciences, general
-
Article
Open AccessPatterns of sequencing coverage bias revealed by ultra-deep sequencing of vertebrate mitochondria
Genome and transcriptome sequencing applications that rely on variation in sequence depth can be negatively affected if there are systematic biases in coverage. We have investigated patterns of local variation...
-
Article
Open AccessWhole genome sequencing of the black grouse (Tetrao tetrix): reference guided assembly suggests faster-Z and MHC evolution
The different regions of a genome do not evolve at the same rate. For example, comparative genomic studies have suggested that the sex chromosomes and the regions harbouring the immune defence genes in the Maj...
-
Article
Open AccessHigh-utility conserved avian microsatellite markers enable parentage and population studies across a wide range of species
Microsatellites are widely used for many genetic studies. In contrast to single nucleotide polymorphism (SNP) and genoty**-by-sequencing methods, they are readily typed in samples of low DNA quality/concentr...
-
Article
Open AccessSequencing of the core MHC region of black grouse (Tetrao tetrix) and comparative genomics of the galliform MHC
The MHC, which is regarded as the most polymorphic region in the genomes of jawed vertebrates, plays a central role in the immune system by encoding various proteins involved in the immune response. The chicke...
-
Article
Open AccessDigital gene expression analysis of the zebra finch genome
In order to understand patterns of adaptation and molecular evolution it is important to quantify both variation in gene expression and nucleotide sequence divergence. Gene expression profiling in non-model or...
