50 Result(s)
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Article
Open AccessEconomic evaluation of anti-CD19 CAR T-cell pathway for large B-cell lymphomas in the real-life setting: the experience of an Italian hub center in the first three years of activity
Poor literature report actual and detailed costs of chimeric antigen receptor (CAR) T-cell pathway in a real-life setting. We retrospectively collect data for all patients with relapsed/refractory aggressive l...
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Article
Open AccessRuxolitinib for the treatment of acute and chronic graft-versus-host disease in children: a systematic review and individual patient data meta-analysis
Steroid-refractory graft-versus-host disease (SR-GvHD) represents a major complication of pediatric allogenic hematopoietic stem cell transplantation. Ruxolitinib, a selective JAK 1–2 inhibitor, showed promisi...
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Article
Letermovir for Cytomegalovirus infection in pediatric patients undergoing allogenic hematopoietic stem cell transplantation: a real-life study by the Infectious Diseases Working Group of Italian Association of Pediatric Hematology-Oncology (AIEOP)
Letermovir prophylaxis revolutionized the approach to Cytomegalovirus infection in adult hematopoietic stem cell transplant (HCT), while data in pediatric setting are still lacking. We retrospectively analyzed...
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Article
Open AccessHealthcare migration in Italian paediatric haematology-oncology centres belonging to AIEOP
In Italy, there is a network of centres headed by the Italian Association of Pediatric Hematology and Oncology (AIEOP) for the diagnosis and treatment of paediatric cancers on almost the entire national territ...
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Current practices for nutritional evaluation and care during the treatment of pediatric oncology patients: a survey among AIEOP centers
Nutritional status plays a crucial role in the mortality rates of the pediatric oncology patients. However, there is a lack of systematic approaches for nutritional assessment in this population. This study ai...
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Article
The Ultrasound Evolution of Lateral Thoracic Perforator Flaps Design and Harvest for Partial and Total Breast Reconstruction
The lateral thoracic area is a known source for perforator flaps for partial breast reconstruction. In this paper, we report our experience in designing and harvesting lateral thoracic perforator flaps for par...
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Article
Response to: meta-analysis on allogeneic transplant for treating pediatric patients with acute myeloid leukemia in first remission: reanalysis of primary data
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Article
Precision surgery for breast cancer: current trends and future perspectives
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Open AccessSecond allogeneic stem cell transplantation can rescue a significant proportion of patients with JMML relapsing after first allograft
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Article
Open AccessERCC6L2-related disease: a novel entity of bone marrow failure disorder with high risk of clonal evolution
ERCC excision repair 6 like 2 (ERCC6L2) gene encodes for different helicase-like protein members of the Snf2 family involved in transcription-coupled nucleotide excision repair and in cell proliferation. Germline...
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Article
Antibiotic prophylaxis and management of infections in pediatric hematopoietic stem cell transplantation: a survey from the Stem Cell Transplant and the Infectious Disease Working Groups of the AIEOP network
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Article
Open AccessAllogeneic hematopoietic stem cell transplantation for pediatric acute myeloid leukemia in first complete remission: a meta-analysis
Identification of pediatric patients with acute myeloid leukemia (AML) candidates to receive allogeneic hematopoietic stem cell transplantation (allo-HSCT) in first complete remission (CR1) is still a matter o...
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Article
Open AccessSafety and Efficacy of Ribociclib in Combination with Letrozole in Patients with HR+, HER2− Advanced Breast Cancer: Results from the Italian Subpopulation of Phase 3b CompLEEment-1 Study
Ribociclib plus letrozole demonstrated manageable safety and efficacy profiles in hormone receptor–positive (HR+), human epidermal growth factor receptor-2–negative (HER2−) advanced breast cancer (ABC) in the ...
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Chapter
Treatment of Chronic Constipation in Pediatrics
Chronic constipation represents a frequent condition in pediatric patients. Causes can be both organic and functional. Treatment for organic causes consists of the treatment of underlying conditions, whereas t...
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Chronic Constipation in Pediatrics: Pathophysiology and Diagnosis
Constipation is one of the most common gastrointestinal symptoms in children. Chronic constipation is defined when symptoms are present for more than 3 months. The key feature required for the diagnosis is red...
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Article
Open AccessHematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome
GATA2 deficiency is a heterogeneous multi-system disorder characterized by a high risk of develo** myelodysplastic syndrome (MDS) and myeloid leukemia. We analyzed the outcome of 65 patients reported to the ...
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Article
Open AccessChromosome X aneusomy and androgen receptor gene copy number aberrations in apocrine carcinoma of the breast
Carcinomas with apocrine differentiation (CAD) of the breast are rare tumours typically presenting high immunohistochemical expression of androgen receptor (AR) which is a target molecule for personalised ther...
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Article
Open AccessAcellular dermal matrix as filler in breast-conserving surgery: warnings for a careful use
Acellular dermal matrices are biological materials of porcine, bovine, or human origin used as scaffold for reconstructive purpose in plastic surgery; these materials are well-tolerated and safely integrated i...
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Article
Compliance with Specific Recommendations and Tasks Reduces Nipple Necrosis Rates in Prepectoral Implant-Based Reconstruction After Nipple-Sparing Mastectomy
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Article
Open AccessThe altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing
Pediatric myelodysplastic syndrome (PMDS) is a very rare and still poorly characterized disorder. In this work, we identified novel potential targets of PMDS by determining genes with aberrant expression, whic...
