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Article
Current practices for nutritional evaluation and care during the treatment of pediatric oncology patients: a survey among AIEOP centers
Nutritional status plays a crucial role in the mortality rates of the pediatric oncology patients. However, there is a lack of systematic approaches for nutritional assessment in this population. This study ai...
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Article
Open AccessScreening for lysosomal diseases in a selected pediatric population: the case of Gaucher disease and acid sphingomyelinase deficiency
GD and ASMD are lysosomal storage disorders that enter into differential diagnosis due to the possible overlap in their clinical manifestations. The availability of safe and effective enzymatic therapies has r...
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Article
Open AccessGAU-PED study for early diagnosis of Gaucher disease in children with splenomegaly and cytopenia
Gaucher disease (GD) diagnosis can be delayed due to non-specific symptoms and lack of awareness, leading to unnecessary procedures and irreversible complications. GAU-PED study aims to assess GD prevalence in...
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Article
Open AccessBaseline liver steatosis has no impact on liver metastases and overall survival in rectal cancer patients
The liver is one of the most frequent sites of metastases in rectal cancer. This study aimed to evaluate how the development of synchronous or metachronous liver metastasis and overall survival are impacted by...
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Article
Open AccessUsing text analysis software to identify determinants of inappropriate clinical question reporting and diagnostic procedure referrals in Reggio Emilia, Italy
Inappropriate prescribing of diagnostic procedures leads to overdiagnosis, overtreatment and resource waste in healthcare systems. Effective strategies to measure and to overcome inappropriateness are essentia...
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Article
Open AccessThe impact of introducing tyrosine kinase inhibitors on chronic myeloid leukemia survival: a population-based study
Chronic myeloid leukemia is associated with a BCR/ABL oncoprotein inhibited by imatinib mesylate, the first tyrosine kinase inhibitor. Although experimental studies have clearly demonstrated the efficacy of im...
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Article
Open AccessTissue Doppler Imaging for anthracycline cardiotoxicity monitoring in pediatric patients with cancer
Cardiotoxic effects of anthracycline therapy are a major cause of morbidity for childhood cancer survivors. The aim of this retrospective evaluation is to assess the efficacy of Tissue Doppler Imaging in the e...
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Article
Trace elements in starter infant formula: dietary intake and safety assessment
The aim of this study was to investigate the concentrations of five essential (Fe, Mn, Zn, Cu and Se) and four non-essential/toxic elements (Cr, Cd, Ni and Pb) in 35 different starter infant formulas (0–6 mont...