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Article
Self-assembled NIPAM–PEG–NIPAM polymeric nanomicelles for the delivery of zinc protoporphyrin: a potential stimuli-triggered cancer treatment approach
Zinc protoporphyrin (ZnPP), known as a heme-oxygenase inhibitor, acts as an anticancer agent mainly by increasing free radical levels in the target cells and inducing cell death. However, its efficacy is restr...
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Article
Teriflunomide Loaded SPION Nanoparticles Induced Apoptosis in MDA-MB-231 Breast Cancer Cells
Teriflunomide (TFN), an immunomodulatory drug, has demonstrated cytotoxic effects in recent studies. This potential can be combined with nano-drug delivery to achieve an improved anticancer formulation.
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Article
Mesoporous silica coated SPIONs containing curcumin and silymarin intended for breast cancer therapy
Super-paramagnetic iron oxide nanoparticles (SPIONs) are known as promising theranostic nano-drug carriers with magnetic resonance imaging (MRI) properties. Applying the herbaceous components with cytotoxic ef...
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Article
Open AccessSN38 loaded nanostructured lipid carriers (NLCs); preparation and in vitro evaluations against glioblastoma
SN38 is the active metabolite of irinotecan with 1000-fold greater cytotoxicity compared to the parent drug. Despite the potential, its application as a drug is still seriously limited due to its stability con...