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Article
Preparation and Thermal Insulation Property of BCN-TiN Composite Aerogels by In-Situ Carbothermal Reduction/Nitridation Method
Non-oxide ceramic aerogel draws increasing attention in area of thermal insulation because of its low density, high temperature resistance and good chemical/thermal stability. Here, a BCN-TiN composite aerogel...
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Article
High-breakdown-voltage (>3000 V) and low-power-dissipation Al0.3Ga0.7N/GaN/Al0.1Ga0.9N double-heterostructure HEMTs with Ohmic/Schottky hybrid drains and Al2O3/SiO2 passivation
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Article
2.29-kV GaN-based double-channel Schottky barrier diodes on Si substrates with high VON uniformity
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Article
Open AccessDoxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation
CRISPR-based toolkits have dramatically increased the ease of genome and epigenome editing. SpCas9 is the most widely used nuclease. However, the difficulty of delivering SpCas9 and inability to modulate its e...
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Article
Open AccessA new and spontaneous animal model for ankylosing spondylitis is found in cynomolgus monkeys
Ankylosing spondylitis is a progressive, disabling joint disease that affects millions worldwide. Given its unclear etiology, studies of ankylosing spondylitis relied heavily on drug-induced or transgenic rode...
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Article
Open AccessWhole-genome sequencing reveals sex determination and liver high-fat storage mechanisms of yellowstripe goby (Mugilogobius chulae)
As a promising novel marine fish model for future research on marine ecotoxicology as well as an animal model of human disease, the genome information of yellowstripe goby (Mugilogobius chulae) remains unknown. H...
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Article
Open AccessDevelopment of a real-time loop-mediated isothermal amplification assay for detection of porcine circovirus 3
Porcine circovirus type 3 (PCV3) is an emerging circovirus species, that has been reported in major pig-raising countries including the United States, China, South Korea, Brazil, Spain, and Poland.
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Article
High-throughput Luminex xMAP assay for simultaneous detection of antibodies against rabbit hemorrhagic disease virus, Sendai virus and rabbit rotavirus
Rabbits are widely used as models in biological research, and the pathogen status of rabbits used in studies can directly affect the results of experiments. Serological surveillance is the common monitoring me...
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Article
Characterization of transcriptional responses mediated by benzo[a]pyrene stress in a new marine fish model of goby, Mugilogobius chulae
Benzo[a]pyrene (BaP) is one of the most studied targets among polycyclic aromatic hydrocarbons (PAHs). Because of the complexity of the toxicity mechanism in BaP, little is known about the molecular mechanism ...
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Article
Open AccessDevelopment and evaluation of a broadly reactive reverse transcription recombinase polymerase amplification assay for rapid detection of murine norovirus
Murine norovirus (MNV) is recognized as the most prevalent viral pathogen in captive mouse colonies. The rapid detection assay for MNV would be a useful tool for monitoring and preventing MNV infection. A reco...
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Article
Open AccessA multiplex xTAG assay for the simultaneous detection of five chicken immunosuppressive viruses
Chicken anemia virus (CAV), avian reovirus (ARV), infectious bursal disease virus (IBDV), Marek’s disease virus (MDV) and reticuloendotheliosis virus (REV) all cause immunosuppressive disease in birds through ...
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Article
Open AccessDevelopment of a sensitive and specific xMAP assay for detection of antibodies against infectious laryngotracheitis and bronchitis viruses
A serological method to simultaneously detect antibodies against infectious laryngotracheitis virus (ILTV) and infectious bronchitis virus (IBV) is imperative for the differential diagnosis and evaluation of a...
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Article
Open AccessRapid detection of three rabbit pathogens by use of the Luminex x-TAG assay
Domestic rabbits especially New Zealand white rabbits play an important role in biological research. The disease surveillance and quality control are essential to guarantee the results of animal experiments pe...
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Article
Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin
Cross-species transmission of viruses from wildlife animal reservoirs poses a marked threat to human and animal health 1 . Bats have been recognized as one of the most important reservoirs for emerging v...
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Article
Open AccessEstablishment and evaluation of four different types of patient-derived xenograft models
Patient-derived xenografts (PDX) have a biologically stable in tumor architecture, drug responsiveness, mutational status and global gene-expression patterns. Numerous PDX models have been established to date,...
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Article
Structural reliability analysis and reliability-based design optimization: Recent advances
We review recent research activities on structural reliability analysis, reliability-based design optimization (RBDO) and applications in complex engineering structural design. Several novel uncertainty propag...
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Article
A nonhuman primate model of Alzheimer’s disease generated by intracranial injection of amyloid-beta42 and thiorphan
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive impairment and neuropathological changes, including the deposition of amyloid-beta (Aβ) peptide. Aged monkeys hav...
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Article
Open AccessRecombination facilitates neofunctionalization of duplicate genes via originalization
Recently originalization was proposed to be an effective way of duplicate-gene preservation, in which recombination provokes the high frequency of original (or wild-type) allele on both duplicated loci. Becaus...
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Article
General expression for linear and nonlinear time series models
The typical time series models such as ARMA, AR, and MA are founded on the normality and stationarity of a system and expressed by a linear difference equation; therefore, they are strictly limited to the line...
