41 Result(s)
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Article
Myocardial Transit Time Map** by CMR: A Novel Indicator of Microcirculatory Dysfunction in Cardiac Amyloidosis
Cardiac amyloidosis (CA) is characterized by the deposition of amyloid fibrils within the myocardium, resulting in a restrictive physiology. Although microvascular dysfunction is a common feature, it is diffic...
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Open AccessDevelopment of postoperative bronchopleural fistula after neoadjuvant immunochemotherapy in non-small cell lung cancer: case reports and review of the literature
The advent of immune checkpoint inhibitors has dramatically changed the treatment paradigm for advanced non-small-cell lung cancer (NSCLC). Due to the complexity and diversity of stage III disease, the inclusi...
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Article
Comparing Strain Assessment in Compressed Sensing and Conventional Cine MRI
The aim of this study is to assess the feasibility of compressed sensing (CS) acceleration methods compared to conventional segmented cine (Seg) cardiac magnetic resonance (CMR) for evaluating left ventricular...
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Article
Open AccessMyocardial involvement characteristics by cardiac MR imaging in neurological and non-neurological Wilson disease patients
To explore the characteristics of myocardial involvement in Wilson Disease (WD) patients by cardiac magnetic resonance (CMR).
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Article
Small-molecule anti-COVID-19 drugs and a focus on China’s homegrown mindeudesivir (VV116)
The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous efforts to develop therapeutic agents that target severe acute respiratory syndrome coronavirus 2 to control viral infection. So far, ...
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Article
Open AccessClinical manifestations and MRI features of Danon disease: a case series
Danon disease (DD) is an exceptionally uncommon X-linked dominant lysosomal glycogen storage disorder characterized by pronounced ventricular hypertrophy and cardiac insufficiency. The timely identification of...
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Article
Open AccessPrognostic factors in patients with thymoma who underwent surgery
Thymoma is the most common primary tumor in the anterior mediastinum. The prognostic factors of patients with thymoma still need to be clarified. In this study, we aimed to investigate the prognostic factors o...
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Open AccessHost Genetic Factors, Comorbidities and the Risk of Severe COVID-19
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was varied in disease symptoms. We aim to explore the effect of host genetic factors and comorbiditi...
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Article
Irisin Regulates Cardiac Responses to Exercise in Health and Diseases: a Narrative Review
Exercise has been recognized as an important non-pharmacological approach for the prevention, treatment, and rehabilitation of cardiovascular diseases, but the mechanisms of exercise in promoting cardiovascula...
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Article
Correction to: Adult‑onset vanishing white matter in a patient with EIF2B3 variants misdiagnosed as multiple sclerosis
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Article
Adult-onset vanishing white matter in a patient with EIF2B3 variants misdiagnosed as multiple sclerosis
Vanishing white matter (VWM) is an autosomal recessive disorder characterized by childhood ataxia with central hypomyelination. Adult-onset VWM should be considered as a differential diagnosis for suspected ca...
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Open AccessTailoring enhanced production and identification of isoflavones in the callus cultures of Pueraria thomsonii Benth and its model verification using response surface methodology (RSM): a combined in vitro and statistical optimization
Scientifically, isoflavones from Pueraria thomsonii Benth possess diverse pharmacological activities and have been used to treat various diseases. In vitro propagation of callus has contributed to the reliability...
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Article
Open AccessClinical characteristics and patient outcomes of molecular subtypes of small cell lung cancer (SCLC)
Recent studies have shown that according to the expression levels of achaete-scute homolog 1 (ASCL1), neurogenic differentiation factor 1 (NEUROD1), and POU class 2 homeobox 3 (POU2F3), small cell lung cancer ...
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Article
Robotic colorectal cancer surgery in China: a nationwide retrospective observational study
Robotic colorectal cancer surgery is widely accepted and applied. However, there is still no objective and comprehensive assessment on the data of nationwide multicenter series.
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Article
Open AccessExercise improves bone formation by upregulating the Wnt3a/β-catenin signalling pathway in type 2 diabetic mice
The bone formation ability of type 2 diabetes is inhibited, and exercise can effectively improve the bone formation of T2DM. However, whether exercise can mediate the Wnt3a/β-catenin pathway to improve the mec...
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Article
N6-methyladenosine demethylase ALKBH5 suppresses malignancy of esophageal cancer by regulating microRNA biogenesis and RAI1 expression
N6-Methyladenosine (m6A) is the most prevalent epigenetic RNA modification and is vital in regulating malignancies. The roles of m6A modifiers on noncoding RNAs have not been fully investigated in esophageal canc...
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Article
Open AccessThe willingness for dietary and behavioral changes in frontline epidemic prevention workers after experiencing the outbreak of COVID-19 in China: a cross-sectional study
The 2019 novel coronavirus disease (COVID-19) has had a massive impact on public health, resulting in sudden dietary and behavioral habit changes. Frontline epidemic prevention workers play a pivotal role agai...
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Article
Clinical and oncological outcomes of single-incision vs. conventional laparoscopic surgery for rectal cancer
To evaluate the clinical and oncological outcomes of single-incision laparoscopic surgery (SILS) vs. conventional laparoscopic surgery (CLS) for patients with rectal cancer (RC) who underwent total mesorectal ...
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Article
Open AccessClinical and radiographic characteristics, management and short-term outcomes of patients with COVID-19 in Wenzhou, China
Coronavirus disease 2019 (COVID-19) is an emerging viral disease. Here, we report the clinical features, management, and short-term outcomes of COVID-19 patients in Wenzhou, China, an area outside Wuhan.
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Article
Open AccessBMI modified the association of current smoking with the incidence of hypertension in Chinese population: a 22-year cohort study
There was little known on how the interaction effect between obesity and current smoking affected the incidence of hypertension. The aim of this study was to investigate how body mass index (BMI) modified the ...
