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  1. Article

    Open Access

    Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

    The cationic lipid Genzyme lipid (GL) 67 is the current "gold-standard" for in vivo lung gene transfer. Here, we assessed, if GL67 mediated uptake of siRNAs and asODNs into airway epithelium in vivo.

    Uta Griesenbach, Chris Kitson, Escudero Sara Garcia, Raymond Farley in Respiratory Research (2006)

  2. No Access

    Article

    Efficient gene transfer to airway epithelium using recombinant Sendai virus

    Clinical studies of gene therapy for cystic fibrosis (CF) suggest that the key problem is the efficiency of gene transfer to the airway epithelium. The availability of relevant vector receptors, the transient ...

    Yoshikazu Yonemitsu, Christopher Kitson, Stefano Ferrari in Nature Biotechnology (2000)