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    Cathepsin B maturation plays a critical role in leptin-induced hepatic cancer cell growth through activation of NLRP3 inflammasomes

    Leptin, an adipose tissue-derived hormone, exhibits potent tumor promoting effects through various mechanisms. Cathepsin B, a member of the lysosomal cysteine proteases, has been shown to modulate the growth o...

    ThiKem Nguyen, Raut Pawan Kumar, Pil-Hoon Park in Archives of Pharmacal Research (2023)