10 Result(s)

Article

Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles

Development of a malaria vaccine that blocks transmission of different parasite stages to humans and mosquitoes is considered critical for elimination efforts. A vaccine using Pfs25, a protein on the surface o...

Nicholas J. MacDonald, Kavita Singh, Karine Reiter, Vu Nguyen… in npj Vaccines (2023)

Article

Author Correction: A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes

Camila H. Coelho, Wai Kwan Tang, Martin Burkhardt, Jacob D. Galson… in Nature Communications (2022)

Article

A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes

Malaria elimination requires tools that interrupt parasite transmission. Here, we characterize B cell receptor responses among Malian adults vaccinated against the first domain of the cysteine-rich 230 kDa gam...

Camila H. Coelho, Wai Kwan Tang, Martin Burkhardt, Jacob D. Galson… in Nature Communications (2021)

Article

Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins

Proteins Pfs230 and Pfs48/45 are Plasmodium falciparum transmission-blocking (TB) vaccine candidates that form a membrane-bound protein complex on gametes. The biological role of Pfs230 or the Pfs230-Pfs48/45 com...

Kavita Singh, Martin Burkhardt, Sofia Nakuchima, Raul Herrera… in Communications Biology (2020)

Article

Induction of PrMADS10 on the lower side of bent pine tree stems: potential role in modifying plant cell wall properties and wood anatomy

The molecular mechanisms underlying inclination responses in trees are unclear. In this study, we identified a MADS-box transcription factor differentially expressed early after inclination in the stems of Pinus ...

Nicolás Cruz, Tamara Méndez, Patricio Ramos, Daniela Urbina… in Scientific Reports (2019)

Article

Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach

The symptoms of malaria are brought about by blood-stage parasites, which are established when merozoites invade human erythrocytes. Our understanding of the molecular events that underpin erythrocyte invasion...

Krishan Kumar, Prakash Srinivasan, Michael J. Nold, J. Kathleen Moch… in Scientific Reports (2017)

Article

XTHs from Fragaria vesca: genomic structure and transcriptomic analysis in ripening fruit and other tissues

Fragaria vesca or ‘woodland strawberry’ has emerged as an attractive model for the study of ripening of non-climacteric fruit. It has several advantages, such as its small genome and i...

María Cecilia Opazo, Rodrigo Lizana, Yazmina Stappung, Thomas M. Davis… in BMC Genomics (2017)

Article

Development and preliminary evaluation of a 90 K Axiom® SNP array for the allo-octoploid cultivated strawberry Fragaria × ananassa

A high-throughput genoty** platform is needed to enable marker-assisted breeding in the allo-octoploid cultivated strawberry Fragaria × ananassa. Short-read sequences from one diploid and 19 octoploid accession...

Nahla V Bassil, Thomas M Davis, Hailong Zhang, Stephen Ficklin… in BMC Genomics (2015)

Article

Gravitropic response in radiata pine seedlings. Searching molecular keys

Patricio Ramos, Nicolas Cruz, Alvaro González, Raúl Herrera in BMC Proceedings (2011)

Article

(Not) Kee** the stem straight: a proteomic analysis of maritime pine seedlings undergoing phototropism and gravitropism

Plants are subjected to continuous stimuli from the environment and have evolved an ability to respond through various growth and development processes. Phototropism and gravitropism responses enable the plant...

Raul Herrera, Catherine Krier, Celine Lalanne, ElHadji Maodo Ba… in BMC Plant Biology (2010)