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Open AccessHakai overexpression effectively induces tumour progression and metastasis in vivo
At early stages of carcinoma progression, epithelial cells undergo a program named epithelial-to-mesenchymal transition characterized by the loss of the major component of the adherens junctions, E-cadherin, w...
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Article
Open AccessRole of the microtubule-targeting drug vinflunine on cell-cell adhesions in bladder epithelial tumour cells
Vinflunine (VFL) is a microtubule-targeting drug that suppresses microtubule dynamics, showing anti-metastatic properties both in vitro and in living cancer cells. An increasing body of evidence underlines the in...