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Article
Open AccessMicroevolution from shock to adaptation revealed strategies improving ethanol tolerance and production in Thermoanaerobacter
The molecular links between shock-response and adaptation remain poorly understood, particularly for extremophiles. This has hindered rational engineering of solvent tolerance and correlated traits (e.g., prod...
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Article
Open AccessStructure and regulation of the cellulose degradome in Clostridium cellulolyticum
Many bacteria efficiently degrade lignocellulose yet the underpinning genome-wide metabolic and regulatory networks remain elusive. Here we revealed the “cellulose degradome” for the model mesophilic celluloly...