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Open AccessDevelopment of finely tuned liposome nanoplatform for macrophage depletion
Immunotherapy with clodronate-encapsulated liposomes, which induce macrophage depletion, has been studied extensively. However, previously reported liposomal formulation-based drugs (Clodrosome® and m-Clodrosome®
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Article
KSNM60: The History of Radiopharmaceutical Sciences in Korea
A number of researchers in Korea have tried to set-up the production of radionuclides and develop new radiopharmaceuticals for several decades. Thanks to their 60-year endeavor to advance the field of radiopha...
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Article
Open Access[18F]FET PET is a useful tool for treatment evaluation and prognosis prediction of anti-angiogenic drug in an orthotopic glioblastoma mouse model
O-2-18F-fluoroethyl-l-tyrosine ([18F]FET) has been widely used for glioblastomas (GBM) in clinical practice, although evaluation of its applicability in non-clinical research is still lacking. The objective of th...
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Identification of a peptide ligand for antibody immobilization on biosensor surfaces
The construction of biosensors with antibodies as the biological sensing element requires the integration of antibodies into the biosensor such that their activity is reproducibly retained. In this work, a pep...
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Open AccessEstablishment of a mouse model of 70% lethal dose by total-body irradiation
Whereas increasing concerns about radiation exposure to nuclear disasters or side effects of anticancer radiotherapy, relatively little research for radiation damages or remedy has been done. The purpose of th...
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Korean red ginseng extract alleviates atherosclerotic lesions in apolipoprotein E knockout mice
This study was to evaluate the anti-atherosclerotic effect of Korean red ginseng (KRG) in apolipoprotein E knockout (ApoE KO) mice. Female ApoE KO mice were divided into 2 groups and were treated via intragast...