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Open AccessRetrospective analysis of neoplasms in patients using angiotensin receptor blockers
In recent years, regulatory agencies have raised concerns about the presence of potentially carcinogenic substances in certain formulations of Angiotensin Receptor Blockers (ARBs). Specifically, nitrosamines a...
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Correction to: Prevalence of Sensory Processing Deficits in Children with Spastic Cerebral Palsy - An Indian Caregiver’s Perspective
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Prevalence of Sensory Processing Deficits in Children with Spastic Cerebral Palsy - An Indian Caregiver’s Perspective: Authors' Reply
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Prevalence of Sensory Processing Deficits in Children with Spastic Cerebral Palsy - An Indian Caregiver’s Perspective
This study aims to analyze the prevalence and patterns of sensory processing deficits (SPD) in Indian children with spastic cerebral palsy (CP) using child sensory profile-2 (CSP-2) caregiver questionnaire. Th...
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Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate
COVID-19 is caused by severe acute respiratory syndrome coronavirus-2, SARS-CoV-2. COVID-19 has changed the world scenario and caused mortality around the globe. Patients who recovered from COVID-19 have shown...
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Open AccessRecent advances in synthetic strategies and SAR of thiazolidin-4-one containing molecules in cancer therapeutics
Cancer is one of the life-threatening diseases accountable for millions of demises globally. The inadequate effectiveness of the existing chemotherapy and its harmful effects has resulted in the necessity of d...
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Repurposing of Immunomodulators for the Treatment of Cancer with QSAR Approaches
Natural products with immunomodulatory activity are widely used to treat many diseases, including autoimmune diseases, inflammatory disorders and other cancer treatments. Over the last decades, the immunomodul...
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Emerging Role of ACE-2 in Cerebrovascular and Neurological Disorders: Lessons Learnt from COVID-19
(RAS) plays a vital role in the maintenance of cardiovascular function and physiology. inhibitors, , and angiotensin-converting enzymes are widely used to treat a wide range of . Identification and decodi...
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Reverse Translational Approach in Repurposing of Drugs for Anticancer Therapy
Cancer treatment costs are rising due to high expense of clinical trials and a low success rate of around 12%. This necessitates cost-effective and safe anticancer medications. Repurposing of existing drugs ma...
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Repurposing of Drugs for the Treatment of Microbial Diseases
The looming threat of rising antimicrobial resistance (AMR) is one of the major threats to public health, and there is an immediate unmet need of discovery and development of new antimicrobial agents. Traditio...
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Emerging Novel Therapies for COVID-19: Implications for the Use of Nitric Oxide as an Anti-COVID-19 Therapy
The pandemic of COVID-19 is an unprecedented calamity that has seriously affected entire human race. The treatment guidelines for COVID-19 were obviously unavailable to the lack of prior data on the mode of tr...
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Organ-on-a-Chip: Novel In Vitro Model for Drug Discovery
In conventional drug discovery process, the attrition in clinical development as a consequence of late clinical trial failure has been very high. One of the main reasons for high attrition rate during clinical...
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Role of ACE2-Ang (1–7)-Mas axis in post-COVID-19 complications and its dietary modulation
Severe acute respiratory syndrome-coronavirus-2 (COVID-19) virus uses Angiotensin-Converting Enzyme 2 (ACE2) as a gateway for their entry into the human body. The ACE2 with cleaved products have emerged as maj...
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Biomarker-Based Drug Discovery with Reverse Translational Approach
The development of new drugs and their approval has become very low as only few molecular entities were approved between 2010 and 2019 with an average of 31 drugs/year between 2010 and 2014 and 44 drugs/year b...
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Therapeutic opportunities of edible antiviral plants for COVID-19
The pandemic of Serious Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) that produces corona virus disease (COVID-19) has challenged the entire mankind by rapidly spreading globally in 210 countries aff...
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Herbal Formulations for the Treatment of COVID-19
COVID-19 has emerged as the most severe pandemic with rapid transmissibility. Initially the pathophysiology was not clear and the drugs and their basis to be used have been a great challenge. Even after over 1...
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Modified Denouement in Bariatric Surgery Due to Genetic Polymorphism
is a major issue and has a of about 13% around the world. Obese patients are prone to have certain diseases like cardiovascular, metabolic disorders and such as breast, endometrial and colon. There are ...
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Role of Liver X Receptor in Cardiovascular Diseases
are the leading cause of death worldwide including various complications and . Looking into the limitations and side effects of interventional and non-interventional treatment strategies, can be the nove...
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Open AccessAnti cancer activity of colon specific osmotic drug delivery of acetone extract of Quercus Infectoria Olivier, Fagaceae in 1,2-dimethylhydrazine-induced colon cancer in rats
