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Article
Open AccessA case of adaptation through a mutation in a tandem duplication during experimental evolution in Escherichia coli
DNA duplications constitute important precursors for genome variation. Here we analyzed an unequal duplication harboring a beneficial mutation that may provide alternative evolutionary outcomes.
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Article
Open AccessThe multiplicity of divergence mechanisms in a single evolving population
Evolutionary divergence is common within bacterial species and populations, even during a single bacterial infection. We use large-scale genomic and phenotypic analysis to identify the extent of diversificatio...
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Article
Open AccessThe uncertain consequences of transferring bacterial strains between laboratories - rpoSinstability as an example
Microbiological studies frequently involve exchanges of strains between laboratories and/or stock centers. The integrity of exchanged strains is vital for archival reasons and to ensure reproducible experiment...
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Article
Insertion Sequence-Driven Evolution of Escherichia coli in Chemostats
Insertion sequence (IS) elements are present in almost all bacterial genomes and are mobile enough to provide genomic tools to differentiate closely related isolates. They can be used to estimate genetic diver...
