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    Chapter

    Metabolomics in the Study of Human Mitochondrial Diseases

    Mitochondria are dynamic cellular organelles playing many biological roles that are fundamentally required for cellular functions. The primary role of mitochondria is ATP production through oxidative phosphory...

    Rajaa Sebaa, Mary-Ellen Harper in Clinical Metabolomics Applications in Gene… (2023)

  2. Article

    Open Access

    Naked mole-rat brown fat thermogenesis is diminished during hypoxia through a rapid decrease in UCP1

    Naked mole-rats are among the most hypoxia-tolerant mammals. During hypoxia, their body temperature (Tb) decreases via unknown mechanisms to conserve energy. In small mammals, non-shivering thermogenesis in brown...

    Hang Cheng, Rajaa Sebaa, Nikita Malholtra, Baptiste Lacoste in Nature Communications (2021)