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    Article

    t(7;12)(q36;p13) and t(7;12)(q32;p13) – translocations involving ETV6 in children 18 months of age or younger with myeloid disorders

    Our retrospective karyotype review revealed two rare recurrent translocations affecting ETV6 (TEL): t(7;12)(q36;p13) and t(7;12)(q32;p13). Five patients with a t(7;12) were from a group of 125 successfully karyot...

    RM Slater, Ev Drunen, WG Kroes, D Olde Weghuis, E van den Berg, EM Smit in Leukemia (2001)

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    MDR1 expression in poor-risk acute myeloid leukemia with partial or complete monosomy 7

    Expression of the multidrug resistance (MDR1) phenotype, encoded by the MDR1 gene, is an adverse prognostic factor for CR and survival in acute myeloid leukemia (AML). Other prognostic factors, such as specific c...

    MM van den Heuvel-Eibrink, EAC Wiemer, MJ de Boevere, RM Slater, EME Smit in Leukemia (2001)

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    Article

    Detection of CBP rearrangements in acute myelogenous leukemia with t(8;16)

    The CREB-binding protein (CBP) is a large nuclear protein that regulates many signal transduction pathways and is involved in chromatin-mediated transcription. The translocation t(8;16)(p11;p13.3) consistently...

    RH Giles, JG Dauwerse, C Higgins, F Petrij, JW Wessels, GC Beverstock, H Döhner in Leukemia (1997)