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Chapter
Exercise Concepts for Fall Prevention
Exercise has been shown to effectively prevent falls in various populations, including healthy community-dwelling older adults as well as frail older adults, or persons with cognitive decline. As falls are the...
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Article
Physical performance among patients aged 70 + in acute care: a preliminar comparison between the Short Physical Performance Battery and the De Morton Mobility Index with regard to sensitivity to change and prediction of discharge destination
The Short Physical Performance Battery (SPPB) and the De Morton Mobility Index (DEMMI) are two commonly used instruments to assess mobility in older patients.
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Article
Influence of fall environment and fall direction on risk of injury among pre-frail and frail adults
In this prospective study, half of all falls resulted in injury. Pre-frail adults sustained more injuries, while more frail adults had injuries requiring hospitalization or fractures. Pre-frail adults fell mor...
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Article
Timeline of functional recovery after hip fracture in seniors aged 65 and older: a prospective observational analysis
We investigated the timeline of functional recovery after hip fracture over 12 months in adults age ≥ 65 years using objective lower extremity function tests and subjective physical functioning. Objective func...
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Article
Effects of a simple home exercise program and vitamin D supplementation on health-related quality of life after a hip fracture: a randomized controlled trial
To test the effects of vitamin D intervention and a simple home exercise program (HE) on health-related quality of life (HRQL) in the first 12 months after hip fracture.
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Article
Calcifediol versus vitamin D3 effects on gait speed and trunk sway in young postmenopausal women: a double-blind randomized controlled trial
In this double-blind RCT, 4-month treatment with calcifediol compared with vitamin D3 improved gait speed by 18 % among young postmenopausal women. Consistently, change in 25(OH)D blood levels over time were sign...
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Article
Gender-specific hip fracture risk in community-dwelling and institutionalized seniors age 65 years and older
In this study of acute hip fracture patients, we show that hip fracture rates differ by gender between community-dwelling seniors and seniors residing in nursing homes. While women have a significantly higher ...
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Article
Before and after hip fracture, vitamin D deficiency may not be treated sufficiently
Our findings show that only about 20 % of seniors receive vitamin D supplementation prior to their index hip fracture or after the event. We further confirm the high prevalence of severe vitamin D deficiency i...
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Article
Bessere Verlaufsdokumentation bei Patienten mit lumboradikulären Schmerzsyndromen
Zweck dieser Studie war es, ein zuverlässiges und einfach anzuwendendes Instrument zur Erfassung des Krankheitsverlaufs und des Therapieerfolgs bei Rückenschmerzpatienten mit lumboradikulären Syndromen vorzust...
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Article
Is fall prevention by vitamin D mediated by a change in postural or dynamic balance?
The objectives were:(1) to validate a quantitative balance assessment method for fall risk prediction; (2) to investigate whether the effect of vitamin D and calcium on the risk of falling is mediated through ...
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Article
Wirkung von Vitamin D auf die Muskulatur im Rahmen der Osteoporose
Eine erfolgversprechende Prävention osteoporotischer Frakturen bei der älteren Bevölkerungsgruppe darf nicht auf eine Verbesserung der Knochendichte beschränkt sein. Ebenso wichtig ist die zusätzliche Sturzprä...
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Article
In Situ Detection of 1,25-dihydroxyvitamin D Receptor In human Skeletal Muscle Tissue
Growing evidence suggests that intracellular vitamin D receptors are present in skeletal muscle tissue mediating vitamin D hormone response. The aim of the work reported here was to investigate the in situ expres...
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Article
Induction of an Acute Attack of Calcium Pyrophosphate Dihydrate Arthritis by Intra-articular Injection of Hylan G-F 20 (Synvisc)
Little is known about the induction of acute calcium pyrophosphate dihydrate arthritis after the intra-articular injection of hylan G-F 20 (Synvisc). Two reports have documented this adverse effect after the ...
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Article
Relationship between muscle strength and vitamin D metabolites: are there therapeutic possibilities in the elderly?
To test the hypothesis that muscle weakness associated with aging is in part due to low serum levels of vitamin D, we investigated the relationship between muscle strength and serum levels of vitamin D metabo...
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Article
Immobility as a Major Cause of Bone Remodeling in Residents of a Long-Stay Geriatric Ward
Residents of a long-stay geriatric ward at the University Hospital Basel were included in a study to investigate the effects of hypovitaminosis D and immobility. All 91 women (mean age 82.5 years) and 92 men (...
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Article
Type I Osteogenesis Imperfecta: Diagnostic Difficulties
A 65-year-old woman presented with vertebral fractures of the lumbar spine and a history of pathological fractures following minor trauma, which had occurred before the onset of menopause. Her past medical hi...
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Article
Interfemur Variation of Bone Mineral Density in Patients Receiving High-dose Thyroxin Therapy
In order to evaluate the interfemoral variability of bone mineral density (BMD) in patients receiving thyroxin (T4) replacement therapy, dual-energy X-ray absorptiometry (DXA) was performed on both hips and t...
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Article
Secondary hyperparathyroidism in hypovitaminosis D is more rapidly suppressed by the administration of 1,25-dihydroxy-vitamin D3 than by vitamin D3
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Article
Alterations in calcium, 25 OH vitamin D, intact parathyroid hormone and total deoxypyridinoline in institutionalized geria tric patients: Relationship to physical activity level
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Article
Comparison of chondroitin sulphate composition of femoral head articular cartilage from patients with femoral neck fractures and osteoarthritis and controls
The glycosaminoglycan (GAG) and uronic acid (UA) composition of human hip articular cartilage from patients with femoral neck fractures [assumed osteoporosis (OP); n=12], from patients with osteoarthritis (OA; n=...