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Article
Open AccessGlyco-engineered anti-EGFR mAb elicits ADCC by NK cells from colorectal cancer patients irrespective of chemotherapy
The epidermal growth factor receptor (EGFR) is overexpressed in colorectal cancer (CRC), and is correlated with poor prognosis, making it an attractive target for monoclonal antibody (mAb) therapy. A component...
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Article
Subcortical nodular heterotopia: a functional MRI and somatosensory evoked potentials study
Subcortical nodular heterotopia (SNH) associated with refractory epilepsy may be surgically treated, and a positive outcome can be expected following the complete excision of the malformed tissue. Recent funct...
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Article
Diagnostic imaging in 13 cases of Rasmussen's encephalitis: can early MRI suggest the diagnosis?
Rasmussen's encephalitis (RE) is a rare, progressive, chronic encephalitis characterised by drug-resistant epilepsy, progressive hemiparesis and mental impairment. It typically involves only one cerebral hemis...
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Article
One hundred years of Golgi’s “perineuronal net”: history of a denied structure
Perineuronal nets are reticular structures enwrap** cell bodies and the largest dendrites of several neuronal populations. Discovered by Camillo Golgi, who described them in detail in 1898, they were intense...
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Article
Glutamate, aspartate and co-localization with calbindin in the medial thalamus An immunohistochemical study in the rat
Topographical and quantitative features of medial thalamic neurons in which aspartate (ASP) or glutamate (GLU) might act as neurotransmitters were investigated in the rat. The calcium-binding protein calbindi...
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Chapter and Conference Paper
Gene Transfer of Suicide Genes for the Treatment of Malignant Gliomas: Efficacy, Limitations, and Perspectives for a Combined Immunotherapy
The potential of gene therapy strategies for malignant gliomas that are based on retroviral-mediated transfer of a “suicide gene” such as Herpes Simplex Virus-thymidine kinase HSV-tk and subsequent treatment b...
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Chapter and Conference Paper
Lesionectomy in Epileptogenic Temporal Lobe Lesions: Preoperative Seizure Course and Postoperative Outcome
A series of 54 patients operated on for temporal epileptogenic lesions is reported: 36 had slow growing tumours, 18 supratentorial cavernous angiomas. The patients were divided into two different groups accord...
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Article
Ultrastructural characterization of the postnatal development of the thalamic ventrobasal and reticular nuclei in the rat
Electron microscopy has been employed to analyze the normal maturationai sequence that characterizes the postnatal development of synaptic circuits in the ventrobasal (VB) and reticular (Rt) thalamic nuclei of...
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Article
Fourth meeting of the European Neurological Society 25–29 June 1994 Barcelona, Spain
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Article
Book reviews
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Article
Distribution of calbindin and parvalbumin in the develo** somatosensory cortex and its primordium in the rat: an immunocytochemical study
Immunocytochemical techniques were used to analyze the distribution of the calcium-binding proteins calbindin and parvalbumin during the pre- and postnatal development of the rat somatosensory cortex. Calbindi...
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Article
Book reviews
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Chapter and Conference Paper
Role of the thalamic reticular nucleus in the generation of rhythmic thalamo-cortical activities subserving spike and waves
The role of the reticular thalamic nucleus (RTN) in pacing rhythmic cortical activities subserving spike-waves (SW) discharges has been investigated in rats.
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Article
GABAergic interneurons and neuropil of the intralaminar thalamus: an immunohistochemical study in the rat and the cat, with notes in the monkey
Immunohistochemistry using antibodies to glutamic acid decarboxylase (GAD) was used to investigate the intralaminar nuclei of the thalamus in rat, cat and monkey. Antibodies to gamma aminobutyric acid (GABA) w...
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Article
Book reviews
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Chapter and Conference Paper
Depth Recording and Neuropathological Aspects in Symptomatic Tumoral and Non Tumoral Epilepsy
Depth EEG recordings have been performed during brain biopsy in 20 epileptic patients with hemispheric deep C.T. scan hypodense lesion. In spite of their epileptic symptomatology, only 3 patients showed “epile...
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Chapter and Conference Paper
Preliminary Results of Specific Thalamic Stimulation for Deafferentation Pain
Ten patients suffering from central or deafferentation pain underwent stereotactic implant of VPM-VPL thalamic nuclei (9 cases) or PVG (1 case). After temporary stimulation trial, 7 patients had definitive imp...
