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    Article

    High sensitivity to carcinogens in the brain of a mouse model of Alzheimer's disease

    Cancer and Alzheimer's disease (AD) are commonly found among elderly patients. Chronic inflammation is the characteristic of both diseases. Amyloid-β peptide is the main inducer of inflammation in AD. Moreover...

    J Serrano, A P Fernández, R Martínez-Murillo, A Martínez in Oncogene (2010)

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    Subcellular localization of low-affinity nerve growth factor receptor-immunoreactive protein in adult rat purkinje cells following traumatic injury

    Cerebellar Purkinje cells in the rat express low-affinity nerve growth factor receptor (p75 NGFR) antigen during development, but rarely in normal adult animals. In striking contrast, re-expression of p75 NGFR...

    R. Martínez-Murillo, Ana P. Fernández, María L. Bentura in Experimental Brain Research (1998)

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    Article

    Chemical heterogeneity in adult rat cerebellar purkinje cells as revealed by zebrin I and low-affinity nerve growth factor receptor immunocytochemical expression following injury

    Cerebellar Purkinje cells in rat express low-affinity nerve growth factor receptor during development, but rarely in normal adult animals. However, after either mechanical injury or colchicine treatment during...

    R. Martínez-Murillo, M. L. Bentura, A. M. Fernandez in Journal of Neurocytology (1995)

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    C-PON immunoreactive neurons in the neostriatum of the hedgehog (Erinaceus europaeus): a correlated light- and electron-microscopic study

    The present study provides light- and electronmicroscopic immunocytochemical data on the presence of neurons that are immunoreactive to the C-terminal flanking peptide of neuropeptide Y, C-PON, in the neostria...

    R. M. Villalba, R. Martínez-Murillo, J. M. Polak, J. Rodrigo in Cell and Tissue Research (1994)

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    Article

    Immunocytochemical analysis of calcitonin gene-related peptide and vasoactive intestinal polypeptide in Merkel cells and cutaneous free nerve endings of cats

    Calcitonin gene-related peptide (CGRP)-and vasoactive intestinal polypeptide (VIP)-immunoreactivity were observed to coexist in Merkel cells of cats. No differences in peptide content were found between Merkel...

    F. J. Alvarez, C. Cervantes, R. Villalba, I. Blasco in Cell and Tissue Research (1988)

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    Article

    Distribution of enkephalin-immunoreactive nerve fibres and terminals in the region of the nucleus basalis magnocellularis of the rat: a light and electron microscopic study

    This investigation was carried out on the distribution of enkephalin-containing nerve fibres and terminals in the region of the nucleus basalis magnocellularis (NBM) of the rat. At the light microscope (LM) le...

    R. Martínez-Murillo, I. Blasco, F. J. Alvarez, R. Villalba in Journal of Neurocytology (1988)

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    Article

    Succinic and malic dehydrogenase histochemical activities in cerebral, cerebellar and neostriatum sections incubated in presence of d-amphetamine

    The action of d-amphetamine on the histochemical activities of succinic and malic dehydrogenases in sections of cerebral cortex, cerebellum, and neostriatum has been studied.

    R. Martínez-Murillo, R. Martínez-Rodriguez, G. Arenas, L. Franic in Acta Neuropathologica (1985)

  8. Article

    Separation of specific fractions of synaptosomes by affinity chromatography

    The authors describe a new technique for isolation of specific fractions of synaptosomes, on the basis of their surface glycoproteins, by affinity chromatography using lectin-Sepharose columns.

    L. M. García-Segura, R. Martínez-Rodríguez, R. Martínez-Murillo in Experientia (1978)