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Open AccessCombining hippocampal volume metrics to better understand Alzheimer’s disease progression in at-risk individuals
To date nearly all clinical trials of Alzheimer’s disease (AD) therapies have failed. These failures are, at least in part, attributable to poor endpoint choice and to inadequate recruitment criteria. Recently...
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K-complexes, spindles, and ERPs as impulse responses: unification via neural field theory
To interrelate K-complexes, spindles, evoked response potentials (ERPs), and spontaneous electroencephalography (EEG) using neural field theory (NFT), physiology-based NFT of the corticothalamic system is used...
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Polygyny in the nest-site limited acacia-ant Crematogaster mimosae
Polygyny is common in social insects despite inevitable decreases in nestmate relatedness and reductions to the inclusive fitness returns for cooperating non-reproductive individuals. We studied the prevalence...
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A new laboratory method for monitoring deep-water coral polyp behaviour
Deep-water corals are found along the oceanic margins world-wide and in the north east Atlantic the most abundant species is Lophelia pertusa (L.). There is now growing evidence that deep-water reefs formed by su...
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Estimating the human health risk from possible BSE infection of the British sheep flock
Following the controversial failure of a recent study1 and the small numbers of animals yet screened for infection2, it remains uncertain whether bovine spongiform encephalopathy (BSE) was transmitted to sheep in...
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Both a ‘magic bullet’ and good aim are required to link public health interests and health care needs in HIV infection
The incomplete distribution of HIV therapy, coupled with uneven HIV transmission rates throughout a population, seem to predict a failure of commodity health care to reduce HIV incidence. Paradoxically, hetero...
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The organizer factors Chordin and Noggin are required for mouse forebrain development
In mice, there is evidence suggesting that the development of head and trunk structures is organized by distinctly separated cell populations1,2. The head organizer is located in the anterior visceral endoderm (A...
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Preparation of Tem Plan View Sections on Specific Devices Using the Tripod Polisher
Plan view or “top down” sections of specific sites for TEM analysis can be prepared by mechanically polishing the specimen with the Tripod Polisher. This technique produces plan view sections with a large area...
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Recent trends in the BSE epidemic
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Correction: Transmission dynamics and epidemiology of BSE in British cattle
Nature 382, 779-788 (1996). In Table 2 of this Letter, the reported number of cases saved for policy 9 was erroneously given for 1996 to 2001 rather than for 1997 to 2001. The number should be 584 rather than ...
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Transmission dynamics and epidemiology of BSE in British cattle
A comprehensive analysis of the bovine spongiform encephalopathy (BSE) epidemic in cattle in Great Britain assesses past, present and future patterns in the incidence of infection and disease, and allows a cr...
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Power laws governing epidemics in isolated populations
TEMPORAL changes in the incidence of measles virus infection within large urban communities in the developed world have been the focus of much discussion in the context of the identification and analysis of no...
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Effect of specimen thickness on the impact resistance of alumina
During the course of an ongoing study into the impact and erosion properties of alumina by the US Bureau of Mines, it was discovered that specimen thickness had a significant effect upon certain fractographic ...
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Books received
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Abstracts of interest
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The spread of HIV-1 in Africa: sexual contact patterns and the predicted demographic impact of AIDS
The spread of HIV-1 in Africa is examined here in the light of recent information on the main epidemiological and behavioural determinants of transmission. Mathematical models incorporating demographic, epidem...
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Potential of community-wide chemotherapy or immunotherapy to control the spread of HIV-1
WHETHER zidovudine (3′-azido-3′-deoxythymidine, AZT) should be offered to symptomless individuals infected with human immunodeficiency virus type-1 (HIV-1), in the hope of delaying or even preventing progressi...
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Sexual lifestyles under scrutiny
Much useful information can be obtained from a knowledge of people's sexual habits, not least information about AIDS. Such studies should be judged by scientists, not by politicians.
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Surveying sexual attitudes
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Estimating the incubation period for AIDS patients