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Article
Commentary on: “Stereotyped activities produced by amphetamine in several animal species and man.” Psychopharmacologia (1967) 11:300–310
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Article
Extrapyramidal reactions and amine metabolites in cerebrospinal fluid during haloperidol and clozapine treatment of schizophrenic patients
8 male schizophrenic patients participated in a double-blind, cross over study of the extrapyramidal side-effects of haloperidol and clozapine (acute dystonia, Parkinsonism and tardive dyskinesia), together wi...
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Article
Short-term effect of perphenazine enanthate on the rat brain
Having previously demonstrated that there is an approximately 20% loss of nerve cells in the basal ganglia (but no loss in the cortex) of rats following the administration of perphenazine enanthate for 12 mont...
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Article
The long-term effect of perphenazine enanthate on the rat brain. Some metabolic and anatomical observations
Perphenazine enanthate 3.4 mg/kg per injection, was administered subcutaneously to rats every second week over a period of a year, a total of 31 mg per animal being given. The animals were observed weekly and ...
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Article
Intrastriatal injection of quaternary butyrophenones and oxypertine: Neuroleptic effect in rats
Bilateral intrastriatal microinjections in rat brains of quaternary neuroleptic drugs of the butyrophenone type (haloperidol, benperidol, floropipamide) and the indole type (oxypertine) antagonize amphetamine-...
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Article
Lesions in corpus striatum and cortex of rat brains and the effect on pharmacologically induced stereotyped, aggressive and cataleptic behaviour
Large bilateral lesions affecting 30–90% of the corpus striatum inhibit stereotyped behaviour in rats injected subcutaneously with amphetamine, but do not prevent rage reactions induced by injection of a monoa...